There is only one "Save Data" database per game so you use Modding.OpenSaveData() - but that db is specific to a particular game.
You can have any number of "User Data" databases as they persist from one game to another. It is recommeneded that the parameters are the mod guid and version, but they don't have to be. All of my "Summary Bar" mods use the same user data db by calling Modding.OpenUserData("SummaryBar", 2) - the 2 indicates my private version number for the layout of the data inside the db
If you just used what you suggested how would it know which db file to open (if you look in the cache you'll find the db files that correspond to the parameters used in the open method)
HTH
W