Thanks, Alan
Civ5 did work on that machine before, which is a 2010 model with the ATI Radeon HD 5770 videocard.
I haven't played Civ in a while, so I wondered what changed in the meantime. The only thing I could think of is the upgrade from 10.6.6 to 10.6.7 and the addition of a 2nd screen (which I disconnected but to no avail).
Here is the part 1 of the error report (my apologies for the length):
Process: Civilization V [43196]
Path: /Volumes/Data1/Users/dvanstraelen/Library/Application Support/Steam/SteamApps/common/sid meier's civilization v/Civilization V.app/Contents/MacOS/Civilization V
Identifier: com.aspyr.Civ5
Version: 1.0.1 (100189)
Code Type: X86 (Native)
Parent Process: launchd [220]
Date/Time: 2011-06-04 17:22:58.537 +0200
OS Version: Mac OS X 10.6.7 (10J869)
Report Version: 6
Interval Since Last Report: 5438338 sec
Crashes Since Last Report: 14
Per-App Interval Since Last Report: 1323 sec
Per-App Crashes Since Last Report: 11
Anonymous UUID: 6598320E-F9C2-45C5-BBC4-2D155185D083
Exception Type: EXC_BAD_ACCESS (SIGBUS)
Exception Codes: KERN_PROTECTION_FAILURE at 0x0000000000000000
Crashed Thread: 0 MainThrd Dispatch queue: com.apple.main-thread
Thread 0 Crashed: MainThrd Dispatch queue: com.apple.main-thread
0 com.aspyr.Civ5 0x000bb5c9 CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 252849
1 com.aspyr.Civ5 0x000bb78d CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 253301
2 com.aspyr.Civ5 0x001e3944 FireGrafix::ResourceList<FireGrafix::FGXConstantSet, 524288u, 512u, 4u>::ReleaseResource(unsigned int) + 7286
3 com.aspyr.Civ5 0x001e6631 FireGrafix::ResourceList<FireGrafix::FGXConstantSet, 524288u, 512u, 4u>::ReleaseResource(unsigned int) + 18787
4 com.aspyr.Civ5 0x003c564f void BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>::UnSubscribe<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >(EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>::SUBSCRIPTION&) + 2391
5 com.aspyr.Civ5 0x003c6a6c void BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>::UnSubscribe<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >(EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>::SUBSCRIPTION&) + 7540
6 com.aspyr.Civ5 0x003c6cff void BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>::UnSubscribe<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >(EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>::SUBSCRIPTION&) + 8199
7 com.aspyr.Civ5 0x003c7237 void BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>::UnSubscribe<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >(EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>::SUBSCRIPTION&) + 9535
8 com.aspyr.Civ5 0x003c7367 void BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>::UnSubscribe<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >(EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>::SUBSCRIPTION&) + 9839
9 com.aspyr.Civ5 0x0039cb1b cvLandmarkVisSystem::SubscribeToEvents() + 1629
10 com.aspyr.Civ5 0x003ae032 FGXModelComponentBuilder_Granny<CvLeaderHeadBufferManagerRendererContext<CvLeaderHeadBuilderContext> >::BuildSurfacesFromModel(FGXModelComponentBuilder_Granny<CvLeaderHeadBufferManagerRendererContext<CvLeaderHeadBuilderContext> >::FGXModelMeshData&, unsigned int, bool) + 320
11 com.aspyr.Civ5 0x003af36b FGXModelComponentBuilder_Granny<CvLeaderHeadBufferManagerRendererContext<CvLeaderHeadBuilderContext> >::BuildSurfacesAndFGXNodesFromModel(granny_model*, unsigned int) + 757
12 com.aspyr.Civ5 0x003af507 FGXModelComponentBuilder_Granny<CvLeaderHeadBufferManagerRendererContext<CvLeaderHeadBuilderContext> >::BuildSurfacesAndFGXNodes(unsigned int) + 255
13 com.aspyr.Civ5 0x003af829 FGXModelComponentBuilder_Granny<CvLeaderHeadBufferManagerRendererContext<CvLeaderHeadBuilderContext> >::Build(std::vector<unsigned int, FSTL_Tagged_Allocator<unsigned int, 4u, 29u, 128u> >*, std::vector<FireGrafix::FGXModelNode, FSTL_Tagged_Allocator<FireGrafix::FGXModelNode, 3u, 29u, 128u> >*, FFastTree<FireGrafix::FGXModelTreeNode, FFastAllocator<FireGrafix::FGXModelTreeNode, false, 29u, 0u, BaseVector<FireGrafix::FGXModelTreeNode, false>::FDefaultFastVectorAllocator> >*, std::vector<FGXVector4, FSTL_Tagged_Allocator<FGXVector4, 4u, 29u, 128u> >*, std::vector<granny_mesh_binding*, FSTL_Tagged_Allocator<granny_mesh_binding*, 4u, 29u, 16u> >*, unsigned int) + 639
14 com.aspyr.Civ5 0x003af8d3 FGXGrannyCompositeContainerBuilderWrapper<CvLeaderHeadBuilderContext, CvLeaderHeadBufferManagerRendererContext>::Build(FGXGrannyCompositeContainerTemplate&, char const**, unsigned int) + 151
15 com.aspyr.Civ5 0x003a80d3 FGXTreeTransformer<FGX_TreeNodeResolver_External<FGXModelTransformer_GrannyDag2Resolver> >::BuildTreeTransforms(unsigned int, FFastTree<FireGrafix::FGXModelTreeNode, FFastAllocator<FireGrafix::FGXModelTreeNode, false, 29u, 0u, BaseVector<FireGrafix::FGXModelTreeNode, false>::FDefaultFastVectorAllocator> >*, CachedGrannyPoseData*) + 10911
16 com.aspyr.Civ5 0x003a81d8 FGXTreeTransformer<FGX_TreeNodeResolver_External<FGXModelTransformer_GrannyDag2Resolver> >::BuildTreeTransforms(unsigned int, FFastTree<FireGrafix::FGXModelTreeNode, FFastAllocator<FireGrafix::FGXModelTreeNode, false, 29u, 0u, BaseVector<FireGrafix::FGXModelTreeNode, false>::FDefaultFastVectorAllocator> >*, CachedGrannyPoseData*) + 11172
17 com.aspyr.Civ5 0x003bed9d CvLeaderHeadShadowMapDX9::Create(unsigned int) + 4203
18 com.aspyr.Civ5 0x003c0266 CvLeaderHeadShadowMapDX9::Create(unsigned int) + 9524
19 com.aspyr.Civ5 0x003c2cd0 FStringA::StripFileExtension(char) + 2524
20 com.aspyr.Civ5 0x0033c21c LinearEventDispatcher<SerialContainer<EventSubscription<fastdelegate::FastDelegate1<EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass>&, void>, NullEventClass> >, EventTemplate<Event_Int2Type<279>, LeaderArtDefineData, LinearEventDispatcher, SerialContainer, NullEventClass, BaseEvent<cvEventSystemSerialAccessor, cvSubscriptionValidator>, NullEventClass> >:

ispatchEvent(unsigned char*, void*) + 53
21 com.aspyr.Civ5 0x0060fdf5 EventDispatcher<EventQueue<EventStream>, DispatchData>:

ispatchEvents(EventStream*, DispatchData*) + 65
22 com.aspyr.Civ5 0x00611e2f EventSystem<EventQueue<EventStream>, SerialEventDispatcher<EventQueue<EventStream>, DispatchData>, cvSerialEventRegistrar, 512u, 4u>:

ublishEvents() + 125
23 com.aspyr.Civ5 0x006063ad void SubscribeToMessage<EventTemplate<Event_Int2Type<35>, VisibilityUpdatedData, LinearEventDispatcher, LocalMachineContainer, NullEventClass, BaseEvent<cvEventSystemLocalMachineAccessor, cvSubscriptionValidator>, NullEventClass>, YieldIconManager, void (YieldIconManager::*)(EventTemplate<Event_Int2Type<35>, VisibilityUpdatedData, LinearEventDispatcher, LocalMachineContainer, NullEventClass, BaseEvent<cvEventSystemLocalMachineAccessor, cvSubscriptionValidator>, NullEventClass>&)>(YieldIconManager*, void (YieldIconManager::*)(EventTemplate<Event_Int2Type<35>, VisibilityUpdatedData, LinearEventDispatcher, LocalMachineContainer, NullEventClass, BaseEvent<cvEventSystemLocalMachineAccessor, cvSubscriptionValidator>, NullEventClass>&)) + 16461
24 com.aspyr.Civ5 0x0025cee5 std::vector<FOutputLocation::FOutputItem, FSTL_Tagged_Allocator<FOutputLocation::FOutputItem, 16u, 35u, 4u> >:

ush_back(FOutputLocation::FOutputItem const&) + 4961
25 com.aspyr.Civ5 0x00614541 cvAudioManager::cvAudioManager() + 577
26 com.aspyr.Civ5 0x000d7adf CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 368839
27 com.apple.HIToolbox 0x9972dc2f DispatchEventToHandlers(EventTargetRec*, OpaqueEventRef*, HandlerCallRec*) + 1567
28 com.apple.HIToolbox 0x9972cef6 SendEventToEventTargetInternal(OpaqueEventRef*, OpaqueEventTargetRef*, HandlerCallRec*) + 411
29 com.apple.HIToolbox 0x9972cd55 SendEventToEventTargetWithOptions + 58
30 com.apple.HIToolbox 0x99761a24 ToolboxEventDispatcherHandler(OpaqueEventHandlerCallRef*, OpaqueEventRef*, void*) + 3006
31 com.apple.HIToolbox 0x9972e080 DispatchEventToHandlers(EventTargetRec*, OpaqueEventRef*, HandlerCallRec*) + 2672
32 com.apple.HIToolbox 0x9972cef6 SendEventToEventTargetInternal(OpaqueEventRef*, OpaqueEventTargetRef*, HandlerCallRec*) + 411
33 com.apple.HIToolbox 0x9974f7f3 SendEventToEventTarget + 52
34 com.apple.HIToolbox 0x998d8c17 ToolboxEventDispatcher + 86
35 com.apple.HIToolbox 0x998d8d4f RunApplicationEventLoop + 243
36 com.aspyr.Civ5 0x000d782b CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 368147
37 com.aspyr.Civ5 0x000d7a6b CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 368723
38 com.aspyr.Civ5 0x00084726 CvWorldBuilderMapModData::~CvWorldBuilderMapModData() + 27918
Thread 1: Dispatch queue: com.apple.libdispatch-manager
0 libSystem.B.dylib 0x97d43922 kevent + 10
1 libSystem.B.dylib 0x97d4403c _dispatch_mgr_invoke + 215
2 libSystem.B.dylib 0x97d434f9 _dispatch_queue_invoke + 163
3 libSystem.B.dylib 0x97d4329e _dispatch_worker_thread2 + 240
4 libSystem.B.dylib 0x97d42d21 _pthread_wqthread + 390
5 libSystem.B.dylib 0x97d42b66 start_wqthread + 30
Thread 2:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 3:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 4:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 5:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 6:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 7:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 8:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 libtbb.dylib 0x082e60ce tbb::internal::rml:

rivate_worker::run() + 478
4 libtbb.dylib 0x082e5ee1 tbb::internal::rml:

rivate_worker::thread_routine(void*) + 17
5 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
6 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 9:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 GLEngine 0x36aea432 gleCmdProcessorPTHREAD + 186
4 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
5 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 10:
0 libSystem.B.dylib 0x97d1d0fa semaphore_timedwait_signal_trap + 10
1 libSystem.B.dylib 0x97d4ac85 _pthread_cond_wait + 1066
2 libSystem.B.dylib 0x97d79aa8 pthread_cond_timedwait_relative_np + 47
3 ...ple.CoreServices.CarbonCore 0x927a6e3d TSWaitOnConditionTimedRelative + 242
4 ...ple.CoreServices.CarbonCore 0x927a6b7b TSWaitOnSemaphoreCommon + 511
5 ...ickTimeComponents.component 0x98cd4591 ReadSchedulerThreadEntryPoint + 4698
6 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
7 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 11:
0 libSystem.B.dylib 0x97d1d0fa semaphore_timedwait_signal_trap + 10
1 libSystem.B.dylib 0x97d4ac85 _pthread_cond_wait + 1066
2 libSystem.B.dylib 0x97d79aa8 pthread_cond_timedwait_relative_np + 47
3 ...ple.CoreServices.CarbonCore 0x927a6e3d TSWaitOnConditionTimedRelative + 242
4 ...ple.CoreServices.CarbonCore 0x927a6b7b TSWaitOnSemaphoreCommon + 511
5 ...ple.CoreServices.CarbonCore 0x928016ee AIOFileThread(void*) + 1127
6 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
7 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 12:
0 libSystem.B.dylib 0x97d1d0fa semaphore_timedwait_signal_trap + 10
1 libSystem.B.dylib 0x97d4ac85 _pthread_cond_wait + 1066
2 libSystem.B.dylib 0x97d79aa8 pthread_cond_timedwait_relative_np + 47
3 com.apple.audio.CoreAudio 0x90a793c7 CAGuard::WaitFor(unsigned long long) + 219
4 com.apple.audio.CoreAudio 0x90a7c3f9 CAGuard::WaitUntil(unsigned long long) + 289
5 com.apple.audio.CoreAudio 0x90a79cf6 HP_IOThread::WorkLoop() + 1892
6 com.apple.audio.CoreAudio 0x90a7958d HP_IOThread::ThreadEntry(HP_IOThread*) + 17
7 com.apple.audio.CoreAudio 0x90a794a4 CAPThread::Entry(CAPThread*) + 140
8 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
9 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 13:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d76ec5 nanosleep$UNIX2003 + 188
2 libSystem.B.dylib 0x97d76e03 usleep$UNIX2003 + 61
3 libMilesX86.dylib 0x08263bbe 0x8263000 + 3006
4 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
5 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 14: AQClient
0 libSystem.B.dylib 0x97d1d09a mach_msg_trap + 10
1 libSystem.B.dylib 0x97d1d807 mach_msg + 68
2 com.apple.CoreFoundation 0x97b8f37f __CFRunLoopRun + 2079
3 com.apple.CoreFoundation 0x97b8e464 CFRunLoopRunSpecific + 452
4 com.apple.CoreFoundation 0x97b8e291 CFRunLoopRunInMode + 97
5 ....audio.toolbox.AudioToolbox 0x98609cfa GenericRunLoopThread::RunLoop() + 60
6 ....audio.toolbox.AudioToolbox 0x9860a0b6 GenericRunLoopThread::Run() + 158
7 ....audio.toolbox.AudioToolbox 0x985cb042 CAPThread::Entry(CAPThread*) + 96
8 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
9 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 15:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d4ad02 _pthread_cond_wait + 1191
2 libSystem.B.dylib 0x97d4c998 pthread_cond_wait$UNIX2003 + 73
3 ....audio.toolbox.AudioToolbox 0x985cab63 CAGuard::Wait() + 93
4 ....audio.toolbox.AudioToolbox 0x985e5f59 AQConverterManager::AQConverterThread::Run() + 399
5 ....audio.toolbox.AudioToolbox 0x985e5faf AQConverterManager::AQConverterThread::ConverterThreadEntry(void*) + 17
6 ....audio.toolbox.AudioToolbox 0x985cb042 CAPThread::Entry(CAPThread*) + 96
7 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
8 libSystem.B.dylib 0x97d4a682 thread_start + 34
Thread 16:
0 libSystem.B.dylib 0x97d4b046 __semwait_signal + 10
1 libSystem.B.dylib 0x97d76ec5 nanosleep$UNIX2003 + 188
2 libSystem.B.dylib 0x97d76e03 usleep$UNIX2003 + 61
3 libMilesX86.dylib 0x08263bbe 0x8263000 + 3006
4 libSystem.B.dylib 0x97d4a7fd _pthread_start + 345
5 libSystem.B.dylib 0x97d4a682 thread_start + 34