The 10 commandments regarding gameplay...
1. Musa needs to die.
The same applies to other too-willing technology brokers. Once I manage to get a tech lead, I don't want everyone else to catch up again by trading.
2. Peace is to be avoided, unless as a last resort.
I will let AIs wear themselves out in unproductive campaigns. Preferably against one another, but having one in permanent war with me is better than letting them build up in peace if conflict is inevitable.
3. Hold the sweat of the labourer more sacred than the ink of the scholar.
I generally focus on production rather than research. On Immortal, I can still win most prizes, on Deity I usually can't afford to chase them.
4. Love the whip.
Previously unhappy people will smile again once you worked half their fellow citizens to death. Essential infrastructure is hard to come by otherwise, particularly so in newly conquered cities.
5. Erect monuments of thy greatness
The best about having a world wonder isn't the bonus or the GPP. It's the knowledge that nobody else has it.
I will eventually dominate my home continent in most games, and one of the more reliable way to impede opponents on other land masses is to deprive them of useful wonders.
6. Live off thy neighbours land
If I can't or don't want to take their cities, I can at least pillage them to the stone age. This will fund my military and cripple them.
7. Aid the weak and the downtrodden
...so they can kick your true rivals in the teeth. Regardless how useless an ally is, a second front can cause even a greater power to stretch their resources too thin.
8. Be frugal with thy precious gold
AIs regard it too lightly and usually consider a 1000

tech for 1000

a fair trade. It isnt. Likewise, if they can afford to pay, I will sell my secrets for cold, hard cash.
9. Trade to avoid trade.
Trading non-monopoly techs freely actually slows don the AI's overall tech pace
10. Never give up.
Whether I start on a tiny barren island or just lost half my empire or Montezuma just spanked me hard with a feather duster, here is usually some enjoyment still to be had with the game.
Also, several seemingly unwinnable games turned out not to be.
Oh, and campy names / painful puns are practically a necessity. If I have near-absolute power, it would be a shame not to abuse it in a childish fashion.