To be honest, I actually thought Beyond Earth would be hugely successful in the multiplayer area precisely because I feel that its gameplay was tuned for multiplayer.
I agree 100% with this but the things that killed Civ:BE multiplayer was that their was a bug which meant MP games would bug out and fail if they could even begin at all.
This was unfortunately one of those bugs that hit at launch and killed the MP scene before it ever had a chance to start.
The bug is fixed now, thankfully, but the damage is done. Furthermore in CivV you could at least pursue a peaceful victory so while war was always a given in MP, it was not the end of the world if you were losing a war as you might win in other ways.
Then thier is the fact that in Civ:BE, war is the
only way to win any of the victory conditions, unlike in CivV. That might not sound like its true but in CivV if you lose all your cities except your capital and are surrounded by enemies, you can still win. Unlikely, sure, but if you are 5/6 spaceship parts you might still win. In Civ:BE you need physical tiles on the map for any VC no matter what so you can't ever come back.
This also compounds 2v1. lets face it, if you are going to play MP you are going to play a few random matches and at some point you are going to fight human players in an offline alliance. In CivV these scenarios are easy to detect by hitting F9 every couple of turns. Who is building a large army? Who is leading in population + science? Is the large army player marching towards you or towards the other player?
In Civ:BE everyone needs an army and their is no F9. So seeing a large roaming army is meaningless and if 2 players ally against you, as I said earlier, you need your land tiles to win so its game over at that point no matter what. They just need to occupy your tiles to stop you building anything you need to win.
Another thing that killed Civ:BE MP was that believe it or not, most players hate having war declared on them. If you consider Civ to be an RTS (it isn't but just pretend) then this is quite baffling but considering you can win without ever building a military unit in CivV, a lot of players will attempt a peaceful victory. Because you can't achieve a peaceful victory in BE unless everyone and the aliens leave you alone and also don't settle too close to you (you may need more tiles, depending on VC) then you are just not going to get a peaceful victory.
Civ games are not an RTS, they are slow methodical games. Even the NQ group that has many rules to streamline games to be faster, will take over an hour to finish a single game. In Civ:BE we also see that Civ games don't make a good RTS, wars are slow and dragged out, even moreso in Civ:BE because all units upgrade at the same time. That is a feature I love, not to make it sound like a negative but their are times in CivV where you are fighting a very close war and take a city by the skin of your teeth and their are times where the enemy finishes a wall and/or builds composite bowmen when you were still using regular archers. The point is moments like that are close and tense and that enhances the gameplay experience.
In Civ:BE we don't get moments like that, you are never barely winning, you either steamroll or stalemate and its boring. Its even more boring when you have spent an hour or two playing the game to only reach a point like this and finally, their is no penalty for leaving. So you can get stuck, start winning and your foe just quits. Its like a punch to the gut, you haven't even taken a city yet (or maybe you have) and then they quit on you. Something that wasn't fixed from CivV