At present, I use the GE from the pyramids to build the GL. I then use 3 GSs to build 3 Acadamy´s in the legendary cities.
I´m not entirely convinced this is worth it. The cultural benefits of the acadamy (+4) are nice to have, but not necessarily worth the expense of a GE, and teching to lit. The +50% science is of course a big bonus, but I seem to be getting my GSs quite late. Indeed, I´m often reasearching Edu/Lib by the time the third one comes, when I´m beginning to think about switching research off.
Another problem with the GL, is that often (not always) I end up getting a fourth GS when what I really want is GAs i.e the GL is messing up my GA pool.
So, I have a number of questions around this.
Should I build the GL?
If I do build the GL, what should I do with the GS? Build academies, or grab new techs to trade e.g. philo, edu?
How should I maximise GS production? Should I have as many scientists in as many cities as possible, or should I concentrate on only having as many scientists as possible in the city with the GL?
If I should build the GL, but the AI beats me to it, is it worth perservering with the game or should I start again?
If I don´t build the GL, what should I do with the GE?
Also, in the city which has the pyramids (which is usually the capital), should I use additional scientists (either before or after the first GE has popped). What I am getting at is should I be trying to preserve the purity of the GE gene pool in the hope of getting a second GE (for the taj majal say), or should I be throwing as much effort at research as possible as early as possible in the game?