As to the Wheel/AH debate...if we research the wheel next we are able to hook up copper, but due to woker turn issues, is not a factor because we shouldn't get the copper hooked up till around turn 48 anyway IMO, to facilitate the growth of the wheat city to size 4 asap (which should happen, if we go fastest, by turn 52, making a total of 67 hammers over 17 turns, hitting size 4 with 1 food remaining or 69 hammers/0 food spare, if my calculations are correct). The wheel does however, allow us to get the settler to the new city site one turn earlier, so all wonders built in that city we get 1 turn sooner, every settler built from that city is settled 1 turn sooner...pretty big deal.
AH allows us to settle the cow city. I like the cow city. It's easier and safer for us to settle. It allows us to see horses, and the best case scenario for the cow city is that it lets us work horses. However, the copper city is a beast, making 16 hammers at size 4; the best the cow city can do is 12hpt, but that requires us to settle at 233 and not 333. If we setle the cow city as the 2nd city but settle at 333, the highest hpt we can get is 9hpt and 1 cottage (and 3fpt) assuming it has horses; due to the cottage requirement, the city can;t hit it's full potential until we have pottery anyway. It also has a lower food per turn output due to only having a grass cow and not an irrigated wheat, making it take a few turns longer to grow to size 4, and even though it is a closer city site, it only gets settled one turn sooner.
The conclusion I draw from this is: the copper city is awesomely powerful as an early game production city We can throw in a barracks (it's a better early site than the capital as the capital 14hpt+2fpt) to make the military and let the capital make the settlers and workers, with the copper city only making workers when military is not required. The cow city is still a good city, but not quite on the same scale; that said, the fastest we can get the third city up and running is turn 44 but that slows the improvement of the copper cities' hills (it could still hit size 4 by turn 52 with copper hooked, and an irrigated plains tile{irrigated wheat (requried for quick growth) but no other hills improved. Still capable of 11h/3fpt), the settler is built 1 turn after we research AH, and that was with AH researched after pottery. So we should settle the copper city first, and that city has no use of AH, but makes use of the wheel. AH is only good for showing us horses, and we will have AH ready before the second settler is complete even if we do wheel next (not sure on pottery though, but are we going to be making cottages?)