The solution to this whole thing is just figuring yourself and not trying to blame it on hormones, drugs or anything else. (afterall, if its drugs, the question is, why are you taking so and so drugs?) And don't blame the pot either. You can smoke a lot of pot and never feel how you do, it's not the pot. It's you.
Ask yourself, why are you depressed? Why do you not like yourself? Why do you not like your life situation? Why do you not want to fix it? And then keep asking the whys and ANSWERING them, figuring it out instead of blaming that mysterious thing called 'depression', which really isn't mysterious at all. You are in control of yourself, and it's up to you to change yourself and your situation, and depend on Yourself to feel good, happy, and all that without validation or approval or attention from others.