I ended up going for a solitaire science game, since it had been a while. 14 cities in total, both barbarian cities were flipped from culture.
In 820 AD I used a Great Merchant to start a Golden Age, after spreading Judaism to my 3 cities that would generate Great Scientists. Used those for Printing Press and Scientific Method.
1010 AD Liberalism -> Communism, but I waited after Guilds and Economics to do a big civic switch (State Property / Free Religion / Caste System) during a second Golden Age, that was started with the free GSpy from Communism and GM from Economics. Got an extra Great Merchant there too for a trade mission.
I moved the Palace to Canterbury after finishing the science buildings (up to Observatory) in London, created an Academy there with a GS and built Oxford in 1180 AD.
After Economics, I went for Replaceable Parts, Chemistry, Steam Power, then eventually Electricity, Assembly Line, and Plastics.
There is no oil or coal on my islands (at least there's aluminium!), so I built the Three Gorges Dam in Canterbury in the late 1600s (whereas the Ironworks are in Liverpool, my main production city). Now in 1700 AD, I have the Apollo Project and I'm starting Superconductors to build Labs, not a record finish but going along smoothly, with no threats from the AI.