Actually I'm experiencing the same thing using CivUP2.4/GEM1.13 (and other mods).
I can activater my mods and start a game fine, but if I go to the main screen (or exit Civ) and try to load the game after the mods menu the game crashes instantly. I dont even see a list of save games to select before it crashes with a DirectX11 error...
Are you able to start a new game, or does that crash too? Civ crashes when attempting to load a savegame made with a different version of Civ. Saves are only compatible with the version of civ you saved it with, so update the game or mods between ending one game and starting the next.
Are you loading modded saves from the Mods -> Next -> Load Game menu?
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