Newsworthy Science

Cultivated meat doesn't require any antibiotics. I guess that never occurred to me before, but that's huge all by itself.

I haven't really read up on this, but this seems dubious to me. When culturing cells in a lab, we almost always use antibiotics in all of the growth media to protect against bacterial infection. Mammalian cell cultures get completely ruined if bacteria get in there, as they're effectively living tissue with pretty much all the working parts of the immune system missing. Growing cells without any antibiotic control is risky, even with the best sterile technique. I have my doubts they'll be able to keep a large enough completely sterile environment to grow tons of meat.
 
I did a little surfing on the subject of cultivated meat. I didn't find a ton with just a quick Googling, and a lot of what I found comes from sources or outlets I've never even heard of before, but here are a couple things. The first one, from Yale in 2016, claims 9 calories in for every calorie out for chicken, but doesn't provide a source, so... :dunno: The second one, from the NIH, is more in-depth and more recent (April of this year), but doesn't provide a calories-for-calories number in the abstract, and I haven't had time to read the whole thing. The NIH study's abstract does note that cultivated meat has an issue with nitrogen in wastewater, which I don't remember being mentioned at all in the podcast I listened to (conventionally-produced meat produces waste water too, but it sounds like cultivated meat is worse, in that regard).

I really really think Yale is wrong, when talking about industrial meat production. The food conversion efficiency is a critical feature of animal farming, and chickens and pigs are much better than that if you keep them inside.
 

USA Today said:
According to the U.S. Department of Agriculture, feral hogs cause approximately $2.5 billion in agricultural damages each year.

Since their introduction to the U.S. in the 1500's, the feral swine population have expanded across more than three quarters of the country. According to the Department of Agriculture, their population has grown to more than 9 million.
USA Today said:
Nearly 300 native plant and animal species in the U.S. are in rapid decline because of feral swine, and many of the species are already at risk, according to Animal and Plant Health Inspection Service.

The swine also carry at least 40 parasites, 30 bacterial and viral illnesses, and can infect humans, livestock and other animals with diseases like brucellosis and tuberculosis.
TB, huh? :twitch: I had to look up brucellosis. It's a bacterial infection that mostly affects cattle and other domestic animals. About 20,000 cases are diagnosed in people every year in the US, which is still considered "very rare" according to the Mayo Clinic.
 
According to the Department of Agriculture, their population has grown to more than 9 million.
If we turn the task of eliminating them over to US gun owners, they should be able to end the problem pretty quickly.
 
If we turn the task of eliminating them over to US gun owners, they should be able to end the problem pretty quickly.
Oh, they're trying. I remember a couple of years ago seeing a video about a farmer in Texas who had a tricked-out AR-15 with a nightvision scope, basically just for shootin' hogs that would chew up his fields at night. Could he have had a suppressor, too? I don't know if those are legal in Texas, but I'd imagine firing a rifle at night would blind you, wouldn't it? And did I see or read something a while back bout people hunting feral pigs from a helicopter? I guess those things can [mess] you up if you get too close. I seem to remember that European boar-hunting spears have those crosspieces behind the blade because a charging boar can get impaled and then just run right up the shaft and gore you in its final moments.

All that said...


Texas Standard said:
Hunting is not only inefficient; it can help spread pigs across the landscape.

“If we were to just go out and hunt them, I liken it to taking a dandelion and blowing on it. You’ve just spread the infestation all across your yard,” said Mike Wefer, wildlife division chief for the Illinois Department of Natural Resources.

Feral hogs move in groups called sounders. The best way to get rid of them is by dispatching the entire sounder at once. This can be accomplished with a corral trap, which surrounds the entire sounder. Shooting them from a helicopter or a hot air balloon is also OK if you can kill the whole group at once.

But if you just shoot one, the rest scatter.
Texas Standard said:
Tennessee is a good example of this. When the state first opened a hunting season on feral hogs in 1999, there were feral hogs in six counties. By 2011, they were in 70 counties.
Texas Standard said:
Other states have even tighter rules for hunting feral hogs. It’s illegal to do so in Utah and Nevada. The same is true in Kansas and Missouri, with a few exceptions. In those places, feral hog numbers have gone down in recent years.

“There have been feral swine in Kansas at least since the early 90s. But we’re a very different model than most places. Sport hunting of feral swine’s never been allowed here. And because of that they’re never really expanded. And I would guess that a lot of Kansans don’t even know we have feral swine in Kansas,” said Drew Ricketts, extension wildlife management specialist with Kansas State University.
 
Ancient Apocalypse or how a volcano erodes?

A 27,000-year-old pyramid? Controversy hits an extraordinary archaeological claim

A headline-grabbing paper1 claiming that a structure in Indonesia is the oldest pyramid in the world has raised the eyebrows of some archaeologists — and has now prompted an investigation by the journal that published it, Nature has learned.

The paper, published in the journal Archaeological Prospection on 20 October, garnered headlines around the world. Its central claim is that a pyramid lying beneath the prehistoric site of Gunung Padang in West Java, Indonesia, may have been constructed as far back as 27,000 years ago.

It’s exactly such claims that have left many fellow researchers cold. Lutfi Yondri, an archaeologist at BRIN in Bandung, Indonesia, says his work has shown that people in the region inhabited caves between 12,000 and 6,000 years ago, long after the pyramid was supposedly built, and no excavations from this period have revealed evidence of sophisticated stonemasonry.

“I'm surprised [the paper] was published as is,” says Flint Dibble, an archaeologist at Cardiff University, UK. He says that although the paper presents “legitimate data”, its conclusions about the site and its age are not justified.

Gunung Padang comprises five stepped stone terraces, with retaining walls and connecting staircases, that sit atop an extinct volcano. Between 2011 and 2014, Natawidjaja and colleagues investigated the site using several ground-penetrating techniques to determine what lies beneath the terraces.

They identified four layers, which they conclude represent separate phases of construction. The innermost layer is a hardened lava core, which has been “meticulously sculpted”, according to the paper.

Subsequent layers of rocks “arranged like bricks” were built over the top of the oldest layer. The layers were carbon-dated, using soil lodged between rocks obtained from a core drilled out of the hill. The first stage of construction, according to the paper, occurred between 27,000 and 16,000 years ago. Further additions were made between 8,000 and 7,500 years ago, and the final layer, which includes the visible stepped terraces, was put in place between 4,000 and 3,100 years ago.

Dibble says that there is no clear evidence that the buried layers were built by humans and were not the result of natural weathering and movement of rocks over time. “Material rolling down a hill is going to, on average, orient itself,” he says. But Natawidjaja says that the column-shaped stones were too large and orderly to have simply rolled there: "The neatly arranged, shaped and massive nature of these rocks, some weighing up to 300 kilograms, dismisses the likelihood of transportation over significant distances."

The authors also report finding a dagger-shaped stone. “This object's regular geometry and distinct composition, and its materials unrelated to the surrounding rocks, signify its manmade origin,” says Natawidjaja. But Dibble says it’s unlikely that the rock was shaped by humans. There's no evidence of “working or anything to indicate that it's man-made”, he says.

The Gunung Padang site featured in the 2022 Netflix documentary Ancient Apocalypse, hosted by British author Graham Hancock, who promotes an idea that an advanced global civilization was wiped out 12,000 years ago at the end of the last ice age. The authors acknowledge Hancock for proofreading their paper.

Natawidjaja says that because Gunung Padang was constructed before the end of the last ice age, it shows that people from that time were capable of building complex structures, and “this makes it a very interesting monument”.

But Bill Farley, an archaeologist at Southern Connecticut State University in New Haven, says the paper has not provided evidence that an advanced civilization existed during the last ice age. The 27,000-year-old soil samples from Gunung Padang, although accurately dated, do not carry hallmarks of human activity, such as charcoal or bone fragments, he says. Archaeological records show that the transition from hunter-gatherer societies to complex societies occupying large settlements occurred after the commencement of the Holocene 11,700 years ago. The oldest known city is the 9,000 year old site of Çatalhöyük in what is now Turkey2.

Archaeological Prospection and its publisher, Wiley, have since launched an investigation into the paper. Eileen Ernenwein, an archaeological geophysicist at Tennessee State University in Johnson City, who is co-editor of the journal said in an email to Nature: “The editors, including me, and Wiley ethics team are currently investigating this paper in accordance with Committee on Publication Ethics guidelines.” She declined to elaborate on the nature of the concerns raised.

Farley says that people should celebrate Gunung Padang for what it is — “an amazing, important and cool site” — rather than because it can be written into any particular narrative about the development of human civilization.

Natawidjaja says that he hopes the controversy does not cause animosity in the community. “We are really open to anyone researchers around the world would like to come to Indonesia and do some research programme on Gunung Padang,” he says. “We know very little about our human history.”

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Spoiler Big pictures from the dig site. I can see why they think them man made. :

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Spoiler Legend :
(a) Aerial view of Gunung Padang taken from a helicopter. (b) Topography and site map generated from a detailed geodetic survey. (c) Geology map of the Gunung Padang region (Sudjatmiko, 1972). (d) Orthophoto map obtained from a drone survey conducted in 2014, indicating the locations of trenching sites (white rectangles) and core-drilling sites (red dots). T1, Terrace 1; T2, Terrace 2; T3, Terrace 3; T4, Terrace 4; T5, Terrace 5.

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Spoiler Legend :
Surface exposures of megalithic stones illustrating two units of construction, Unit 1 (#1) and Unit 2 (#2). (a) South-facing view of T1 landscape, revealing a stone floor and standing columnar rocks of #1, as well as the exposed #2 ramp and altar. (b) North-facing view from T2 onto T1. (c) Columnar rock arrangement example of #1. (d) Unit 2 on the ramp between T1 and T2, showcasing columnar rock fragments enclosed in a fine-grained mortar. (e) Columnar rock wall of #1 construction encircling the margin of T1. (f) Tango trench on T1 exposing the thinly buried #2 columnar rock, aligned in N70°E similar to those on the ramp. (g) Southward view of T2, T3, T4 and T5. (h) Overhead photo of T2 and T3, demonstrating the N55°E alignment of #2 columnar rock with a truncation line. (i) GPR survey uncovering #1 step-stone terraces on the east slope.

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Spoiler Legend :
Beta-2 cliff exposures on the west slope. (a) Field photo and interpreted stratigraphy of the subsurface layers. (b) Side view highlighting Unit 2 and its distinct boundary with the underlying Unit 3. (c) Plan view of Unit 2, showcasing the alignment of columnar rocks enclosed in a fine-grained mortar. (d) Photo displaying planar rock fragments inserted between columnar rocks. (e) Photo featuring a weathered vertical pillar composed of highly weathered columnar rocks surrounded by fine-grained materials.

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Spoiler Legend :
Results of geo-archaeological trenching. (a) Fanta trench: A1. Columnar rock alignment visible on the surface of T2, A2. Oblique view revealing underground continuation of columnar rock alignments (#2), A3. Front profile of #2 columnar rocks exhibiting various sizes and shapes, encased in a 5-cm-thick mortar. (b) Charlie1 trench on the east slope: B1. N70E-oriented columnar rock alignment (#2) dipping 15° towards the slope, B2. Cross-section drawing of Charlie1 trench. (c) Trenching Echo2: C1. East–west cross-section drawing of Echo2 trench, C2. Oblique view displaying buried Unit 3 rock wall, C3. Front view of steep wall comprising highly weathered columnar rock alignment. (d) Delta trench on the south slope: D1. Drawing of the trench, D2. Photo revealing rounded, highly weathered rock fragments buried by homogeneous soil fill. (e) Trenching Charlie2 on the east slope: N70E alignment of non-columnar, blocky rock fragments enclosed in mortar. FC-5, Charlie1-3,4,5, EM-4 and ES-1 represent sample locations for radiocarbon analysis.


 
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These magnificent purple and green lights aren’t auroras. This is Steve​

By Jackie Wattles, CNN

Published 8:57 AM EST, Tue November 28, 2023

Not all science is carried out by folks in white lab coats under the fluorescent lights of academic buildings. Occasionally, the trajectory of the scientific record is forever altered inside a pub over a pint of beer. Such is the case for the sweeping purple and green lights that can hover over the horizon in the Northern Hemisphere. The phenomenon looks like an aurora but is in fact something entirely different.

It’s called Steve.

The rare light spectacle has caused a bit of buzz this year as the sun is entering its most active period, ramping up the number of dazzling natural phenomena that appear in the night sky — and leading to new reports of people spotting Steve in areas it does not typically appear, such as parts of the United Kingdom. But about eight years ago, when Elizabeth MacDonald, a space physicist at NASA’s Goddard Space Flight Center, was in Calgary, Alberta, for a seminar, she had never seen the phenomenon in person. And it did not yet have a name.

Pictures and more at the link.

 
Chinstrap penguins are the best animals at napping

Dozing off while reading a book or working at a computer is a familiar experience to many of us. Birds are also known to engage in these ‘microsleeps’ — but one species seems to have mastered the art of the brief slumber.

Chinstrap penguins (Pygoscelis antarcticus) nod off more than 10,000 times a day for an average of 4 seconds at a time, researchers have found. The short snoozes, which add up to more than 11 hours of daily sleep, seem to be enough to fulfil at least some of the restorative functions of sleep, according to a study published today in Science.

The authors studied 14 penguins nesting in a colony on King George Island, Antarctica. Over 10 days of observation, the birds never engaged in prolonged sleep. The longest nap registered was 34 seconds. “This is what was the most striking and interesting — the fact that they can deal with sleeping in a fragmented way continuously, day and night,” says co-author Paul-Antoine Libourel, a sleep ecophysiologist at the Neuroscience Research Center of Lyon in Bron, France.

To collect data on brain activity, the researchers implanted electrodes inside the penguins’ skulls. This allowed the scientists to identify when the birds entered a state of slow-wave sleep, which is the dominant form of sleep in birds and also occurs in humans.

Penguins engaged in more than 600 short bouts of slow-wave sleep per hour. These bouts became even shorter and more frequent when the birds were caring for eggs, perhaps because they need to be more alert while incubating, the researchers say.

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Cybernetic brains heal quicker / better

Electrodes placed inside the brains of five people with traumatic injuries improved their performance in attention and memory tests.

The technique known as deep brain stimulation (DBS) has improved cognition in people with traumatic brain injuries, a small clinical trial has found.

The trial data, published in Nature Medicine on 4 December1, show that the five participants had a 15–52% improvement in their processing speed in a cognitive test after three months compared to their performance before the DBS implants.

“For some participants, the improvements have been transformative, even many years after the injury,” says study co-author Jaimie Henderson, a neurosurgeon at Stanford University in California.

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A coloured MRI scan of a brain because it is pretty
 
Dolphins feel electric fields

Bottlenose dolphins (Tursiops truncatus) can sense electricity using the pits left behind when the whiskers they are born with fall out. “Everybody thought these structures are vestigial — so without any function,” said zoologist and study co-author Guido Dehnhardt. His team trained two captive dolphins to place their snouts near submerged electrodes and swim away when they detected an electric field. The researchers found that the dolphins’ sensitivity to electricity was similar to that of platypuses. Electroreception could help the animals to find fish hiding in sand on the sea floor or to navigate the ocean using Earth’s magnetic field.

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Spoiler Full article :

Newborn bottlenose dolphins sport a row of hairs along the tops of their jaws. But once the animals are weaned, the whiskers fall out.

“Everybody thought these structures are vestigial — so without any function,” said Guido Dehnhardt, a marine mammal zoologist at the University of Rostock in Germany.

But Dr. Dehnhardt and his colleagues have discovered that the pits left by those hairs can perceive electricity with enough sensitivity that they may help the dolphins snag fish or navigate the ocean. The team reported its findings Thursday in The Journal of Experimental Biology.

Dr. Dehnhardt first studied the whisker pits of a different species, the Guiana dolphin. He expected to find the typical structures of hair follicles, but those were missing. Yet the pits were loaded with nerve endings. He and his colleagues realized that the hairless follicles looked like the electricity-sensing structures on sharks and found that one Guiana dolphin responded to electrical signals. They wondered whether other toothed cetaceans, including bottlenose dolphins, could also sense electricity.

For the new study, the researchers trained two bottlenose dolphins to rest their jaws, or rostrums, on a platform and swim away anytime they experienced a sensory cue like a sound or a flash of light. If they didn’t detect one of these signals, the dolphins were to stay put.
“It’s basically the same as when we go to the doctor’s and do a hearing test — we have to press a button as soon as we hear a sound,” said Tim Hüttner, a biologist at the Nuremberg Zoo in Germany and a study co-author.

Once trained, the dolphins also received electrical signals. “The dolphins responded correctly on the first trial,” Dr. Hüttner said. The animals were able to transfer what they had learned, revealing that they could also detect electric fields. Further study showed that the dolphins’ sensitivity to electricity was similar to that of the platypus, which is thought to use its electrical sense for foraging.


Sharks are far more sensitive to electric fields, which they use up close after they have chased down prey by smell from a distance. But the electrosense might also aid dolphins for a close grab at fish while they’re hunting. The dolphins spot prey with their eyes and by sending clicking sounds that bounce off prey, known as echolocation. But fish bodies also produce electrical fields through the activity of their muscles and gills.

Such signals could help the dolphins home in on prey hiding on the seafloor. Bottlenose dolphins perform what’s called crater feeding, said Denise Herzing, a marine mammalogist at the Wild Dolphin Project in Florida who wasn’t involved with the study. “They dig,” she said. “They put their beaks down into the sand, almost up to the eyeballs, and pull out these eels.” Sand may make it harder for dolphins to detect buried fish through echolocation, she said.

Other researchers urged caution. The study used two dolphins, and “we do not know whether this ability is actually used in the wild,” said Juliana López-Marulanda, a marine biologist at University Paris Nanterre.

Dolphins may also use electrosensitivity to navigate. Dr. López-Marulanda and others have observed that dolphins can sense magnetic fields. Because they have bits of magnetic material in their bodies, the electric sense may allow them to feel changes in the Earth’s magnetic field and use something like a magnetic map.

Dr. Dehnhardt wonders if electrosensing may explain mass strandings of healthy whales and dolphins. Researchers have noticed links between shifts of the magnetic field, such as during solar storms, and mass strandings. “This may, for the first time, explain on a sensory basis how this really occurs,” he said. Such strandings don’t occur in baleen whales that — unlike their toothed cousins — use the whiskers they’re born with across their lives, he noted.

Understanding dolphin senses better could help protect the animals, Dr. López-Marulanda said. For instance, once sharks’ electrosensitivity was discovered, some fishing fleets added electromagnetic devices to nets to keep sharks away. Perhaps something similar may be possible with dolphins, although they are much less sensitive, she said.

For an animal that has received plenty of research attention, it’s exciting to spot a new sense.
“Everything has been worked on this species,” Dr. Dehnhardt said. “And still there is something new that we can discover.”
 
Hawking - Penrose singularity proof is WRONG!!!!

Roy Kerr, who figured out the maths of rotating black holes, has found a "simple" error in the proof that black holes must have a singularity that Steven Hawking and Roger Penrose came up with 50 years ago. The proof was not compatible with quantum mechanics so was probably "wrong" anyway but it seems pretty big to me.

Spoiler Abstract :
There is no proof that black holes contain singularities when they are generated by real physical bodies. Roger Penrose claimed sixty years ago that trapped surfaces inevitably lead to light rays of finite affine length (FALL's). Penrose and Stephen Hawking then asserted that these must end in actual singularities. When they could not prove this they decreed it to be self evident. It is shown that there are counterexamples through every point in the Kerr metric. These are asymptotic to at least one event horizon and do not end in singularities.

Spoiler Youtube reference :
 
Australian Indigenous genomes are highly diverse and unlike those anywhere else

Australian Indigenous communities are some of the most genetically distinct people on the planet, with the highest rate of genetic variation outside groups in Africa. A new pair of studies sought permission from 159 Indigenous Australians to add their genetic data to global databases, and found that as much as 12% of structural variants — variations that are at least 50 base pairs in size — are unique to these communities. The information will help to provide better health care for Indigenous Australians and others across the world.

Spoiler Article :
Australian Indigenous communities from different regions in the north and centre of the country are some of the most genetically distinct people on the planet, according to a pair of studies published in Nature today. Indigenous Australian communities have the highest rate of genetic variation outside people in Africa.

Hundreds of thousands of human genomes have been sequenced since the Human Genome Project was launched in 1990, yet very few of these genomes are from Indigenous Australians.

“The history of genetic research has not proven to be kind to the interests of Indigenous and other diverse communities around the globe,” says study co-author Alex Brown, an Indigenous Australian from the Yuin nation and director of the National Centre for Indigenous Genomics at the Australian National University in Canberra.

As a result, Indigenous Australians are substantially under-represented in the genomic data sets that now underpin much research in medicine.

“Those data sets don’t contain any information about Indigenous peoples, and that creates bias in our interpretation of genomics,” says Hardip Patel, a co-author of both papers and a bioinformatics researcher at the National Centre for Indigenous Genomics.

There are health implications, too. Without Indigenous genomes in reference data sets, diagnosing genetic diseases in these groups is difficult. “If you’re trying to diagnose an Indigenous patient with a genetic disease, you’re comparing them to the wrong reference data set,” says Ira Deveson, a clinical genomics researcher at the Garvan Institute of Medical Research in Sydney, Australia.

However, the high degree of genomic variation between communities suggests that researchers need to do much more work to fully represent Australian Indigenous genetic diversity in these data sets, he says. “We actually need to cast the net wide and try to capture as many of the different community groups that are living in this country if we’re going to have truly inclusive reference data that will actually work,” he says.

Genetically distinct

One of the new studies, which was led by the National Centre for Indigenous Genomics, has taken a step towards addressing that bias by sequencing the genomes of 159 individuals from geographically separate, remote Indigenous communities in four locations: the Tiwi Islands and Elcho Island, off the coast of the Northern Territory; Yarrabah in Queensland; and Titjikala in the central desert region. These were compared with a reference panel of individuals from Australia, Papua New Guinea, Eurasia and Africa. This analysis suggested that, as a whole, Indigenous Australians have almost as much genetic variation as Africa, but in some communities, particularly those on the Tiwi Islands, there is a relatively low rate of genetic variation.

The level of variation between Indigenous Australians and individuals from Papua New Guinea differed between communities, but suggested that the two populations diverged around 47,000 years ago.
 
Researchers create 'Mugatu,' the first steerable bipedal robot with only one motor

What I found interesting was that one of the team members was an undergrad who only had a vague understanding of MATLAB when he started working with them yet contributed towards the robot's sensor. I feel some kind of sympathy, having to do a frantic crash course in MATLAB just to submit a Linear Algebra assignment. Not the same thing of course, but still. Must be nice to work with a team while polishing your understanding and skills. It's so cold here
 
US nuclear-fusion lab enters new era: achieving ‘ignition’ over and over

This year, the US National Ignition Facility (NIF) has lived up to its name by achieving ignition using lasers — not once, but four times. Ignition is a nuclear reaction that creates more energy than it consumes, similar to the hydrogen-fusion process that powers the Sun. The success created buzz at the COP28 climate conference this month and led to US$42 million of funding for three new US research centres dedicated to the dream of practically limitless clean energy. But the NIF was never designed to generate power (it’s for studying fusion reactions as they relate to nuclear weapons). “We now know it will work,” says physicist Carmen Menoni. “What will take time is to develop the technology to a level where we can build a power plant.”

Spoiler Article :
In December 2022, after more than a decade of effort and frustration, scientists at the US National Ignition Facility (NIF) announced that they had set a world record by producing a fusion reaction that released more energy than it consumed — a phenomenon known as ignition. They have now proved that the feat was no accident by replicating it again and again, and the administration of US President Joe Biden is looking to build on this success by establishing a trio of US research centres to help advance the science.

The stadium-sized laser facility, housed at the Lawrence Livermore National Laboratory (LLNL) in California, has unequivocally achieved its goal of ignition in four out of its last six attempts, creating a reaction that generates pressures and temperatures greater than those that occur inside the Sun.

“I’m feeling pretty good,” says Richard Town, a physicist who heads the lab’s inertial-confinement fusion science programme at the LLNL. “I think we should all be proud of the achievement.”

The NIF was designed not as a power plant, but as a facility to recreate and study the reactions that occur during thermonuclear detonations after the United States halted underground weapons testing in 1992. The higher fusion yields are already being used to advance nuclear-weapons research, and have also fuelled enthusiasm about fusion as a limitless source of clean energy. US special presidential envoy for climate John Kerry called for new international partnerships to advance fusion energy at the COP28 climate summit in Dubai last week, and the US Department of Energy (DOE), which oversees the NIF, followed up by announcing the new research hubs, to be led by the LLNL, the University of Rochester in New York and Colorado State University in Fort Collins.

Building the NIF was “a leap of faith” for many, and its success has had a real impact on the fusion community, as well as on public perception, says Saskia Mordijck, a physicist at William & Mary, a university in Willamsburg, Virginia. “In that sense, what is important is that scientists said they could do something, and then they actually did do something.”

Hot shots

The NIF works by firing 192 laser beams at a frozen pellet of the hydrogen isotopes deuterium and tritium that is housed in a diamond capsule suspended inside a gold cylinder. The resulting implosion causes the isotopes to fuse, creating helium and copious quantities of energy. On 5 December 2022, those fusion reactions for the first time generated more energy — roughly 54% more — than the laser beams delivered to the target.

The facility set a new record on 30 July when its beams delivered the same amount of energy to the target — 2.05 megajoules — but, this time, the implosion generated 3.88 megajoules of fusion energy, an 89% increase over the input energy. Scientists at the laboratory achieved ignition during two further attempts in October (see ‘A year of progress’). And the laboratory’s calculations suggest that two others in June and September generated slightly more energy than the lasers provided, but not enough to confirm ignition.

For many scientists, the results confirm that the laboratory is now operating in a new regime: researchers can repeatedly hit a goal they’ve been chasing for more than a decade. Tiny variations in the laser pulses or minor defects in the diamond capsule can still allow energy to escape, making for an imperfect implosion, but the scientists now better understand the main variables at play and how to manipulate them.

“Even when we have these issues, we can still get more than a megajoule of fusion energy, which is good,” says Annie Kritcher, the NIF’s lead designer on this series of experiments.

New hubs

It’s a long way from there to providing fusion energy to the power grid, however, and the NIF, although currently home to the world’s largest laser, is not well-suited for that task. The facility’s laser system is enormously inefficient, and more than 99% of the energy that goes into a single ignition attempt is lost before it can reach the target.

Developing more efficient laser systems is one goal of the DOE’s new inertial-fusion-energy research programme. This month, the agency announced US$42 million over four years to establish three new research centres — each involving a mix of national laboratories, university researchers and industry partners — that will work towards this and other advances.

This investment is the first coordinated effort to develop not just the technologies, but also the workforce for a future laser-fusion industry, says Carmen Menoni, a physicist who is heading up the hub at Colorado State University.

So far, most government investments in fusion-energy research have gone towards devices known as tokamaks, which use magnetic fields inside a doughnut-shaped ‘torus’ to confine fusion reactions. This is the approach under development at ITER, an international partnership to build the world’s largest fusion facility near Saint-Paul-lez-Durance, France. Tokamaks have also been the focus of many fusion investments in the private sector, but dozens of companies are pursuing other approaches, such as laser fusion.

The timing for a dedicated laser-fusion programme is right, says Menoni, and the decision to pursue it wouldn’t have happened without the NIF’s recent success. “We now know it will work,” she says. “What will take time is to develop the technology to a level where we can build a power plant.”

Back at the NIF, Kritcher’s latest series of experiments features a 7% boost in laser energy, which should, in theory, lead to even larger yields. The first experiment in this series was one of the successful ignitions, on 30 October. Although it didn’t break the record, an input of 2.2 megajoules of laser energy yielded an output of 3.4 megajoules of fusion energy.

Kritcher chalks up the fact that it didn’t break the record for energy yield to growing pains with the new laser configuration, which is designed to squeeze more energy into the same gold cylinder. Before moving to a larger cylinder, Kritcher says her team is going to focus on changes to the laser pulse that could produce a more symmetrical implosion. “We’ve got four experiments next year,” she says. “Let’s see.”


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At the US National Ignition Facility in Livermore, California, 192 lasers (beamlines shown here) run into a target chamber (highlighted in blue) and focus on a capsule containing hydrogen isotopes.
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A new class of antibiotics is cause for cautious celebration — but the economics must be fixed

The bacterium Acinetobacter baumannii is a portrait of resilience. The microorganism causes a range of infections, and its ability to survive desiccation means it can persist for weeks on hospital air vents, computer keyboards and human skin. Its metabolic and genetic flexibility have allowed it to become resistant to the few antibiotics that can make it through its two protective cell membranes. Antibiotic-resistant microbes kill more than one million people each year. The global threat posed by A. baumannii has put the microbe high on the list of priority pathogens drawn up by the World Health Organization (WHO).

Two studies published on 3 January in Nature report a new class of drug candidates for tackling A. baumannii infections (C. Zampaloni et al. and K. P. Pahil et al.). One of these compounds has already made it into clinical trials, but it is still a long way from being approved for clinical use.

The obstacles for developing such compounds are not just scientific: the economic incentives are insufficient for many companies to take the risk. As the threat of resistance grows, the international community must do more to shepherd promising drugs from bench to bedside.

The new compounds block the bacterium’s ability to shuttle key building blocks to where they are needed, and do so by binding to a novel site in the bacterium — there are other compounds that target this pathway, but A. baumannii is resistant to them. One of the molecules, called zosurabalpin, killed multiple resistant strains of A. baumannii in culture, and, in mice, a strain resistant to all available antimicrobials. The first clinical-trial results for the compound are expected this year.

It is rare to get antibiotics with a new mode of action into the clinic — only one in 30 candidates makes it as far as testing in people. Even when a new drug does get through clinical trials and is approved for use, it is often held in reserve for worst-case scenarios, for fear that widespread use would hasten the day when microbes develop resistance to it.

Clearing the initial phase of clinical trials will be only the beginning. Further studies will then be needed to assess the risk of resistance to zosurabalpin emerging in clinical settings. Then, if the drug is approved, someone will need to pay for it. The commercial market is dismal by design. A new antibiotic often costs more than US$1 billion to develop, but the reluctance to use it widely means that it is likely to earn less than $100 million a year once on the market. The WHO and others have warned governments about the scale of the expense, coupled with the growing threat of antimicrobial resistance. Some governments have responded with incentives to encourage industry to take up the challenge. But there has been much more talk than action.

The solution, health economists say, is a mix of incentives for new antimicrobial drug development. ‘Push’ strategies are designed to reduce the costs and can include more government funding for early-stage research. ‘Pull’ approaches reward companies for developing successful antibiotics — for example, governments might guarantee a minimum level of purchase, similar to the advanced purchases made of vaccines during the COVID-19 pandemic. Governments have tended to lean more towards push strategies. Economists say they need to do more pulling. But they must also heed lessons learnt from COVID-19 vaccines, such as ensuring that pricing and contracts are transparent, which did not happen during the pandemic.

The United Kingdom has been a leader in this regard. In 2019, it launched a ‘subscription’ programme through which companies are paid a fixed annual fee that is based on a drug’s value to the health-care system, rather than on the number of doses sold. Other countries are considering similar plans. In the United States, a bipartisan team of lawmakers is backing the Pioneering Antimicrobial Subscriptions to End Upsurging Resistance (PASTEUR) Act, which would create a similar programme. But the act has struggled in the US Congress since it was first introduced in 2020. The European Union has also been unable to pass relevant legislation. It is time for governments to move from consideration to action.

Some hesitation is understandable: the subscription model would put further pressure on health-care budgets that are already feeling the strain of drug prices fuelled by high levels of inflation. But there’s another way to look at such payments: as insurance against future health-care crises. If governments can make the market for these drugs viable, that will also encourage companies to invest.
 
Immigration makes Europeans who we are

Even down to our height and propensity for diabetes and MS

More than 1,600 ancient genomes have helped to trace the roots of a host of genetic traits found in modern Europeans. The genomes suggest that many characteristics — including a heightened risk for multiple sclerosis — were carried to Europe by people who migrated to the continent in three distinct waves starting around 45,000 years ago.

These results and others were published today in four related papers in Nature.

The findings provide evidence that some of the regional variation in certain traits was caused by differences in migrants’ dispersal patterns. That contradicts the idea that genetic differences arose mainly as people adapted to conditions in specific locations in Europe.

“This is a tour de force,” says Lluís Quintana-Murci, a population geneticist at the Pasteur Institute in Paris who was not involved in the study. He says that the research provides unprecedented detail on how ancient ancestry can influence disease risk to this day. “It’s a beautiful example of how, by addressing very basic fundamental anthropological and genomic questions, you can inform medicine,” he says.

New arrivals

Europe was settled by anatomically modern humans in three main waves: hunter-gatherers reached Europe from Asia around 45,000 years ago; farmers arrived from the Middle East 11,000 years ago; and pastoralists — animal herders — came from the steppes of western Asia and eastern Europe 5,000 years ago. Archaeologists and historians had assumed that these groups mixed with one another throughout the continent, and that populations in particular places evolved distinct traits in response to their local environments.

But when geneticist Eske Willerslev at the University of Cambridge, UK, and his team began investigating the ancient-human genomes, they found that that wasn’t the full story. The researchers collected and sequenced DNA from 317 ancient skeletons found in Europe, most of which were between 3,000 and 11,000 years old1. They then combined these sequences with existing genomic data from more than 1,300 other ancient Eurasians.

By comparing the remains’ genetic markers, ages and burial locations, the scientists were able to draw a European family tree and migration map that revealed how genomic characteristics in a specific location changed as populations moved over time1. It showed, for instance, that the steppe pastoralists mainly went to the more northern parts of Europe, whereas the Middle Eastern farmers went to the south and west.

Some of these migrants completely replaced existing populations. Denmark, for instance, underwent two large population transitions, each within just a few generations2. Willerslev says that archaeological evidence and the speed of the transition suggest that the newcomers killed all the locals rather than driving them out or mixing with them.

Of genes and geography

The dispersal patterns mean that many modern Europeans carry some genetic ancestry from all three population waves, but the relative amount of each varies depending on the location, Willerslev says.

Next, the researchers compared the ancient genomes with those of 410,000 modern individuals whose genetic profiles are stored in the UK Biobank, a massive database of genetic and physical information3. The data provided clear evidence that many traits trace back directly to one of the three migration waves.

For instance, modern northern Europeans are taller and lighter skinned than their southern counterparts because they have more ancestry from the steppe pastoralists. And those with the most hunter-gatherer ancestry, commonly found in northeastern Europe, have variants that put them at higher risk of diabetes and Alzheimer’s disease.

“A lot of the history was created outside Europe,” Willerslev says. But once these migrants settled in geographically isolated areas of Europe, these variants became cemented in individual populations.

The study helped to solve questions such as why human adults evolved the ability to digest milk before Europeans herded animals. Mutations near the gene encoding lactase, the enzyme that allows babies to process milk, could have helped early humans to survive famines even before the arrival of the pastoralists. These mutations might have primed the genome for development of the variant that allows lactase to continue to function in adults.

But it’s unclear whether other traits, such as height, provided any advantage to the people who carried them, Willerslev says.

Evolutionary mysteries

That ambiguity does not surprise Tony Capra, an evolutionary geneticist at the University of California, San Francisco. “It’s just really, really hard to know what drives selection,” he says. Although it can be tempting to conclude that a genetic variant was an evolutionary adaptation to an environment, sometimes it is just the result of who was living there at the time, Capra notes. “Even with these amazing windows into the past that ancient DNA gives us, it just underscores what a complex process human evolution has been.”

Coloured scanning electron micrograph (SEM) of multiple sclerosis, microglial cells ingesting oligodendrocytes.
In people with multiple sclerosis, immune cells (round, artificially coloured) attack nervous-system cells called oligodendrocytes (branching structures).Credit: Professor John Zajicek/Science Source Library

Surprisingly, one of the traits that seems to have had a strong evolutionary advantage is one associated with a predisposition to multiple sclerosis. This trait arrived in Europe with the west-Asian pastoralists and became even more common in northern Europe over the subsequent millennia.

Today, multiple sclerosis is a devastating disease caused by an overactive immune system attacking the nervous system. But that superpowered immune system, or genetic variants associated with it, could have helped ancient people to survive plagues and common pathogens, Willerslev says. “That’s the best explanation we can come up with.”

Capra says that the team has taken a “clever” approach to understanding ancient humans by looking at how ancestry affects modern traits, rather than trying to figure out the traits by looking only at ancient-DNA samples. The next step, he and Quintana-Murci say, will be for researchers to apply the methods developed by Willerslev and his colleagues to genomes from other parts of the world, such as southeast Asia and the Americas.

4LRahrt.png

Spoiler Legend :
a–e, Maps showing the average ancestry of: Western hunter-gatherer (WHG) (a); Eastern hunter-gatherer (EHG) (b); Caucasus hunter-gatherer (CHG) (c); Neolithic farmer (d); and Steppe pastoralist (e) ancestry components per country (left) and per county or unitary authority within Great Britain and per country for the Republic of Ireland and Northern Ireland (right). Estimation was performed using ChromoPainter and NNLS, on samples of a ‘typical ancestral background’ for each non-UK country (n = 24,511) and Northern Ireland. For Great Britain, an average of self-identified ‘white British’ samples was used to represent each UK county and unitary authority, based on place of birth (n = 408,884). Countries with less than 4 and counties with less than 15 samples are shown in grey. Map uses ArcGIS layers World Countries Generalized and World Terrain.

Spoiler More pictures :
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Spoiler Legend :
Maps showing networks of highest IBD sharing (top 10 highest sharing per individual) during different time periods for 579 imputed genomes predating 3,000 cal. BP and located in the geographical region shown. Shading and thickness of lines are scaled to represent the amount of IBD shared between two individuals. In the earliest periods, sharing networks exhibit strong links within relatively narrow geographical regions, representing predominantly close genetic ties between small HG communities, and rarely crossing the East–West divide extending from the Baltic to the Black Sea. From around 9,000 cal. BP onwards, a more extensive network with weaker individual ties appears in the south, linking Anatolia to the rest of Europe, as early Neolithic farmer communities spread across the continent. The period 7,000–5,000 cal. BP shows more connected subnetworks of western European and eastern/northern European Neolithic farmers, while locally connected networks of HG communities prevail on the eastern side of the divide. From c. 5,000 BP onwards the divide finally collapses, and continental-wide genetic relatedness unifies large parts of western Eurasia.

gVNI8XF.png

Spoiler Legend :
Quantitative admixture model used to simulate genomes to train the local ancestry neural network classifier. The model begins with the Out-of-Africa population, before splitting into basal Northern Europeans (NE) and West Asians (WA), who further split into EHG, WHG, CHG and ANA. These then admix to form Steppe pastoralist (Yam) and Neolithic farmer (Neo) populations. Moving down the figure is forwards in time and the population split times and admixture times are given in generations ago. Each branch is labelled with the effective population size of the population. Coloured lines represent the populations declared in the simulation that extend through time.

 
Old DN A hints at why MS affects some Europeans
‘What we found surprised everyone,’ said study co-author from Cambridge
BY LAURAN NEERGAARD ASSOCIATED PRESS

WASHINGTON — Ancient DNA helps explain why northern Europeans have a higher risk of multiple sclerosis than other ancestries: It’s a genetic legacy of horseback-riding cattle herders who swept into the region about 5,000 years ago.
The findings come from a huge project to compare modern DNA with that culled from ancient humans’ teeth and bones — allowing scientists to trace both prehistoric migration and disease-linked genes that tagged along. When a Bronze Age people called the Yamnaya moved from the steppes of what are now Ukraine and Russia into northwestern Europe, they carried gene variants that today are known to increase people’s risk of multiple sclerosis, researchers reported Wednesday. Yet the Yamnaya flourished, widely spreading those variants. Those genes probably also protected the nomadic herders from infections carried by their cattle and sheep, concluded the research published in the journal Nature. “What we found surprised everyone,” said study co-author William Barrie, a genetics researcher at the University of Cambridge. “These variants were giving these people an advantage of some kind.” It’s one of several findings from a first-of-its-kind gene bank with thousands of samples from early humans in Europe and western Asia, a project headed by Eske Willerslev of Cambridge and the University of Copenhagen who helped pioneer the study of ancient DNA. Similar research has traced even earlier cousins of humans such as Neanderthals.

Using the new gene bank to explore MS was a logical first step. That’s because while MS can strike any population, it is most common among white descendants of northern Europeans and scientists have been unable to explain why. The potentially disabling disease occurs when immune system cells mistakenly attack the protective coating on nerve fibers, gradually eroding them. It causes varying symptoms — numbness and tingling in one person, impaired walking and vision loss in another — that often wax and wane.

It’s not clear what causes MS although a leading theory is that certain infections could trigger it in people who are genetically susceptible. More than 230 genetic variants have been found that can increase someone’s risk.
The researchers first examined DNA from about 1,600 ancient Eurasians, mapping some major shifts in northern Europe’s population. First, farmers from the Middle East began supplanting hunter-gatherers and then, nearly 5,000 years ago, the Yamnaya began moving in — traveling with horses and wagons as they herded cattle and sheep.

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The process of ancient DNA extraction is shown at the Lundbeck Foundation GeoGenetics Center in Copenhagen. MIKAL SCHLOSSER/ UNIVERSITY OF COPENHAGEN

The research team compared the ancient DNA to about 400,000 present-day people stored in a UK gene bank, to see the MS-linked genetic variations persist in the north, the direction the Yamnaya moved, rather than in southern Europe.
In what is now Denmark, the Yamnaya rapidly replaced ancient farmers, making them the closest ancestors of modern Danes, Willerslev said. MS rates are particularly high in Scandinavian countries. Why would gene variants presumed to have strengthened ancient immunity later play a role in an autoimmune disease? Differences in how modern humans are exposed to animal germs may play a role, knocking the immune system out of balance, said study co-author Dr. Astrid Iversen of Oxford University.

The findings finally offer an explanation for the north-south MS divide in Europe but more work is needed to confirm the link, cautioned genetic expert Samira Asgari of New York’s Mount Sinai School of Medicine, who wasn’t involved with the research, in an accompanying commentary.
 
Oldest photosynthesis more than three time the age of previous record holder

Researchers have identified photosynthetic structures inside fossils of cyanobacteria that are 1.75 billion years old. The discovery is the oldest evidence of these structures to date, providing clues into how photosynthesis evolved.

Emmanuelle Javaux at the University of Liège in Belgium and her colleagues analysed fossils collected from rocks at three sites. The oldest site was the roughly 1.75-billion-year-old McDermott Formation in Australia, and the other two were the billion-year-old Grassy Bay Formation in Canada and the Bllc6 formation in the Democratic Republic of the Congo.

From these rocks, the researchers extracted fossilised cyanobacteria, which produce energy through photosynthesis. “They’re very tiny, less than a millimetre, so you cannot see them with your eyes,” says Javaux. She and her colleagues placed the fossils in resin and sliced them into 60 to 70-nanometre-thick sections using a diamond-edged knife, and then analysed the internal structures with an electron microscope.

They found that the cyanobacteria from Australia and Canada contained thylakoids, or membrane-bound sacs where photosynthesis occurs. “These are the oldest fossilised thylakoids that we know of today,” says Javaux. Previously, the oldest thylakoid fossils were about 550 million years old. “So, we pushed back the fossil record by 1.2 billion years,” she says.

This is important because not all cyanobacteria have thylakoids, and it is unclear when these structures, which made photosynthesis more efficient, first evolved, says Kevin Boyce at Stanford University in California. We can now date this diversification to at least 1.75 billion years ago, he says. The oldest fossils of cyanobacteria are about 2 billion years old, though other evidence, like geochemical signatures, indicate photosynthesis has been around for even longer than that.

It is widely believed that cyanobacteria drove the accumulation of oxygen in Earth’s atmosphere 2.4 billion years ago. “One idea is that, perhaps, they invented thylakoids at this time, and this increased the quantity of oxygen on Earth,” says Javaux. “Now that we’ve found very old thylakoids and that they can be preserved in very old rocks, we think that we could go further back in time and try to test this hypothesis,” she says.

Spoiler Light micrographs of the whole organisms :
6FZdnMM.png

Spoiler Legend :
Images of N. majensis microfossils. a, N. majensis (n = 16) from the McDermott Formation, Tawallah Supergroup, northern Australia. b, N. majensis (n = 22) from the Grassy Bay Formation, Shaler Supergroup, Arctic Canada. c, N. majensis (n = 13) from the BIIc6 Formation, Mbuji-Mayi Supergroup, DRC. One representative specimen for each formation. n, number of measured specimens. Scale bars, 50 µm.



Spoiler Electron micrographs of the photosynthetic apparatus :
yxMYdEZ.png
Spoiler Legend Left figure :
TEM images of N. majensis from the McDermott Formation, Australia, and the Grassy Bay Formation, Canada. a,b, Specimen from the McDermott Formation, Australia (n = 2). a,Well-defined contorted layers are interpreted as thylakoids. Each thylakoid comprises one medium-electron-dense layer surrounded by two electron-dense layers. b, Another part of the section, showing the electron-light outer layer (red arrow) overlying the very thin dark layers (yellow arrow), interpreted as the cell wall. c,d, Specimen from the Grassy Bay Formation, Canada (n = 2). End of the specimen (c)andintermediate region of the specimen (d), both showing well-preserved layers separated by white linear spaces (lumen) and interpreted as thylakoids with their concentric and parietal arrangement. The hole in the centre is the intracellular space. Possible partitions are visible between thylakoids, some possibly merged during diagenesis and burial compression (see also Extended Data Fig.1b). The electron-light outer layer (red arrow in c) overlying the very thin dark layers (yellow arrow in c) is interpreted as the cell wall. n, number of specimens observed by TEM. Scale bars, 200 nm (a,b), 500 nm (c,d).
Spoiler Legend Right figure :
TEM images of N. majensis from the Grassy Bay Formation, Canada, and the BIIc6 Formation, DRC. a,b, Specimens from the Grassy Bay Formation (n = 2). a, The electron-light outer layer (red arrows) overlying the very thin dark layer (yellow arrows), both forming the cell wall; and the partition between stacked thylakoids, seen as lines of small, white holes. b, The complete transversal ultrathin section of a specimen, its length corresponding to microfossil width and its thickness corresponding to that of the flattened microfossil (Extended Data Fig.4). c,d, Specimens from the BIIc6 Formation (n = 2). c, A homogeneous, medium-dense, inner layer surrounded by the outer wall. d, The outer wall comprises an electron-light outer layer (red arrow) that appears to be fibrous (black arrow) overlying the very thin dark layer (yellow arrow). Scale bars, 200 nm (a,d), 5 µm (b), 500 nm (c).
 

Huge ancient city found in the Amazon​

A huge ancient city has been found in the Amazon, hidden for thousands of years by lush vegetation.

The discovery changes what we know about the history of people living in the Amazon.

The houses and plazas in the Upano area in eastern Ecuador were connected by an astounding network of roads and canals.

The area lies in the shadow of a volcano that created rich local soils but also may have led to the destruction of the society.

While we knew about cities in the highlands of South America, like Machu Picchu in Peru, it was believed that people only lived nomadically or in tiny settlements in the Amazon.

"This is older than any other site we know in the Amazon. We have a Eurocentric view of civilisation, but this shows we have to change our idea about what is culture and civilisation," says Prof Stephen Rostain, director of investigation at the National Centre for Scientific Research in France, who led the research.

"It changes the way we see Amazonian cultures. Most people picture small groups, probably naked, living in huts and clearing land - this shows ancient people lived in complicated urban societies," says co-author Antoine Dorison.

The city was built around 2,500 years ago, and people lived there for up to 1,000 years, according to archaeologists.

It is difficult to accurately estimate how many people lived there at any one time, but scientists say it is certainly in the 10,000s if not 100,000s.

The archaeologists combined ground excavations with a survey of a 300 sq km (116 sq mile) area using laser sensors flown on a plane that could identify remains of the city beneath the dense plants and trees.

This LiDAR technology found 6,000 rectangular platforms measuring about 20m (66 ft) by 10m (33 ft) and 2-3m high.

They were arranged in groups of three to six units around a plaza with a central platform.

The scientists believe many were homes, but some were for ceremonial purposes. One complex, at Kilamope, included a 140m (459 ft) by 40m (131 ft) platform.

They were built by cutting into hills and creating a platform of earth on top.

A network of straight roads and paths connected many of the platforms, including one that extended 25km (16 miles).

Dr Dorison said these roads were the most striking part of the research.

"The road network is very sophisticated. It extends over a vast distance, everything is connected. And there are right angles, which is very impressive," he says, explaining that it is much harder to build a straight road than one that fits in with the landscape.

He believes some had a "very powerful meaning", perhaps linked to a ceremony or belief.

The scientists also identified causeways with ditches on either side which they believe were canals that helped manage the abundant water in the region.

There were signs of threats to the cities - some ditches blocked entrances to the settlements, and may be evidence of threats from nearby people.

Researchers first found evidence of a city in the 1970s, but this is the first time a comprehensive survey has been completed, after 25 years of research.

It reveals a large, complex society that appears to be even bigger than the well-known Mayan societies in Mexico and Central America.

"Imagine that you discovered another civilisation like the Maya, but with completely different architecture, land use, ceramics," says José Iriarte, a professor of archaeology at University of Exeter, who was not involved in this research.

Some of the findings are "unique" for South America, he explains, pointing to the octagonal and rectangular platforms arranged together.

The societies were clearly well-organised and interconnected, he says, highlighting the long sunken roads between settlements.

Not a huge amount is known about the people who lived there and what their societies were like.

Pits and hearths were found in the platforms, as well as jars, stones to grind plants and burnt seeds.

The Kilamope and Upano people living there probably mostly focussed on agriculture. People ate maize and sweet potato, and probably drank "chicha", a type of sweet beer.

Prof Rostain says he was warned against this research at the start of his career because scientists believed no ancient groups had lived in the Amazon.

"But I'm very stubborn, so I did it anyway. Now I must admit I am quite happy to have made such a big discovery," he says.

The next step for the researchers is understanding what lies in an adjoining 300 sq km (116 sq mile) area not yet surveyed.
https://www.bbc.com/news/science-environment-67940671
 

Huge ancient city found in the Amazon​

A huge ancient city has been found in the Amazon, hidden for thousands of years by lush vegetation.

The discovery changes what we know about the history of people living in the Amazon.

The houses and plazas in the Upano area in eastern Ecuador were connected by an astounding network of roads and canals.

The area lies in the shadow of a volcano that created rich local soils but also may have led to the destruction of the society.

While we knew about cities in the highlands of South America, like Machu Picchu in Peru, it was believed that people only lived nomadically or in tiny settlements in the Amazon.

"This is older than any other site we know in the Amazon. We have a Eurocentric view of civilisation, but this shows we have to change our idea about what is culture and civilisation," says Prof Stephen Rostain, director of investigation at the National Centre for Scientific Research in France, who led the research.

"It changes the way we see Amazonian cultures. Most people picture small groups, probably naked, living in huts and clearing land - this shows ancient people lived in complicated urban societies," says co-author Antoine Dorison.

The city was built around 2,500 years ago, and people lived there for up to 1,000 years, according to archaeologists.

It is difficult to accurately estimate how many people lived there at any one time, but scientists say it is certainly in the 10,000s if not 100,000s.

The archaeologists combined ground excavations with a survey of a 300 sq km (116 sq mile) area using laser sensors flown on a plane that could identify remains of the city beneath the dense plants and trees.

This LiDAR technology found 6,000 rectangular platforms measuring about 20m (66 ft) by 10m (33 ft) and 2-3m high.

They were arranged in groups of three to six units around a plaza with a central platform.

The scientists believe many were homes, but some were for ceremonial purposes. One complex, at Kilamope, included a 140m (459 ft) by 40m (131 ft) platform.

They were built by cutting into hills and creating a platform of earth on top.

A network of straight roads and paths connected many of the platforms, including one that extended 25km (16 miles).

Dr Dorison said these roads were the most striking part of the research.

"The road network is very sophisticated. It extends over a vast distance, everything is connected. And there are right angles, which is very impressive," he says, explaining that it is much harder to build a straight road than one that fits in with the landscape.

He believes some had a "very powerful meaning", perhaps linked to a ceremony or belief.

The scientists also identified causeways with ditches on either side which they believe were canals that helped manage the abundant water in the region.

There were signs of threats to the cities - some ditches blocked entrances to the settlements, and may be evidence of threats from nearby people.

Researchers first found evidence of a city in the 1970s, but this is the first time a comprehensive survey has been completed, after 25 years of research.

It reveals a large, complex society that appears to be even bigger than the well-known Mayan societies in Mexico and Central America.

"Imagine that you discovered another civilisation like the Maya, but with completely different architecture, land use, ceramics," says José Iriarte, a professor of archaeology at University of Exeter, who was not involved in this research.

Some of the findings are "unique" for South America, he explains, pointing to the octagonal and rectangular platforms arranged together.

The societies were clearly well-organised and interconnected, he says, highlighting the long sunken roads between settlements.

Not a huge amount is known about the people who lived there and what their societies were like.

Pits and hearths were found in the platforms, as well as jars, stones to grind plants and burnt seeds.

The Kilamope and Upano people living there probably mostly focussed on agriculture. People ate maize and sweet potato, and probably drank "chicha", a type of sweet beer.

Prof Rostain says he was warned against this research at the start of his career because scientists believed no ancient groups had lived in the Amazon.

"But I'm very stubborn, so I did it anyway. Now I must admit I am quite happy to have made such a big discovery," he says.

The next step for the researchers is understanding what lies in an adjoining 300 sq km (116 sq mile) area not yet surveyed.
https://www.bbc.com/news/science-environment-67940671
I came here to post this myself. :thumbsup: Really makes you realize that legends like El Dorado or Percy Fawcett's "City Z" were probably legit.
 
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