My advice for a beginner would be to use Rome actually, as you get a free monument in every new city you found. A monument is usually a good idea ASAP in your expands because early culture is so valuable to get you down the civics tree for the better policies and governments.
As a new player to Civ VI, I'd suggest you start with a scout followed by some early military, including a second warrior and a slinger. It will give you a cushion in the early game until you get a feel for things. Then start expanding by building settlers. Beeline Early Empire and slot the "Colonization" card to build them faster. Try and get 5-6 cities by turn 60 to start out. 10-12 by turn 100. Beeline Bronze Working to reveal iron. If you don't have any near your starting location send some settlers to iron locations and build a mine so you begin accumulating resources. Then go after Iron Working so you may upgrade your warriors to Legions.
Let your scout explore the map with the intent on never returning home. Your initials warriors and slingers should circle wide of your starting location picking off barbs and fending off pesky neighbors, while scouting your future expansions.
Eye a couple of early campus locations around mountains, geo thermal fissures, and/or reefs. That will get your science off to a decent start. Put your commercial hubs next to rivers and build the markets asap so you get the trade route capacity. Theater Squares should go next to wonders if possible, but if not just plop as many as you can down next to the government plaza and call it a day. Sell off all of your early luxuries to the AI for gold - you don't need amenities early. As Rome, you get 1 gpt for each internal trading post your traders pass through. Run international trade routes (including one to your future target) but start them on the opposite end of your empire so the trade routes pass through as many of your cities as possible to increase the per turn gold value of the route.
Save up ~600 gold to upgrade 4 warriors to Legions. You can build additional Legions for follow up units. But 4 is a good start along with archers and a battering ram to knock down walls. Remember the trade route you sent your neighbor? Now there's a road for your troops to travel over.
I'd suggest Gamer Grampz' guide on district placement. You can find him on Youtube. The Game Mechanic is on Twitch and Youtube and is very new player friendly. Sorry there's a lot of generalization to this, but there's not a definitive build order. Experience will teach you. Your districting will improve over time. But think of this: you need to expand early, build early defense/future offense, and proper district placement.