cramstpuee757
Chieftain
- Joined
- Apr 30, 2014
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- 32
(37)GamerzPlanet(dead)
Quick! Hit ctrl(or command)+v, number 2
- Thread starter choxorn
- Start date
Bratmon
Super Bratmon 3
Who's the guy to the right of James?
SamSniped
DJ Goodboye
CivDad
King of Garama
Trefain Faerefaen
hoplitejoe
Top fun-poster
- Joined
- Mar 22, 2010
- Messages
- 5,470
Fred Banks?
SamSniped
DJ Goodboye
Hoplitejoe: where is sam when you need him...
CivDad
King of Garama
b͍̓̋ͮͬ̿̉ͨy̨̩̖͉͇͈̯ͩͅl̟̩͕̮̞̼̔̎ͥͣ͞
SamSniped
DJ Goodboye
#28 in Aerospace / Aeronautical / Astronautical Engineering
SS-18 ICBM
Oscillator
Arrow Gamer
America's Dictator
SamSniped
DJ Goodboye
ú
(5char)
(5char)
hoplitejoe
Top fun-poster
- Joined
- Mar 22, 2010
- Messages
- 5,470
hiting those pipes and the rollers girl
SamSniped
DJ Goodboye
mosher94: well you see
mosher94: It was sunday
mosher94: sunday morning
mosher94: so lazy day
mosher94: Some guy left his thing of vaseline on the latrine counter
mosher94: and when he went and retrieved it he noticed there was a giant glob of it missing
mosher94: so a few guys climbed over the stall door to where our friend Lee was in there
mosher94: singing Honky Tonk
mosher94: while honkying his tonk
mosher94: with vaseline
mosher94: It was sunday
mosher94: sunday morning
mosher94: so lazy day
mosher94: Some guy left his thing of vaseline on the latrine counter
mosher94: and when he went and retrieved it he noticed there was a giant glob of it missing
mosher94: so a few guys climbed over the stall door to where our friend Lee was in there
mosher94: singing Honky Tonk
mosher94: while honkying his tonk
mosher94: with vaseline
hoplitejoe
Top fun-poster
- Joined
- Mar 22, 2010
- Messages
- 5,470
SamSniped
DJ Goodboye
Verarde
Pondering Wearing A Hat
hoplitejoe
Top fun-poster
- Joined
- Mar 22, 2010
- Messages
- 5,470
Eladril
SS-18 ICBM
Oscillator
1.) Trichoplein (or mitostatin) is a keratin-binding protein that mediates anchoring of microtubules (MTs) to centrosomes and suppresses primary cilia. It is downregulated in prostate, bladder, and breast cancers. It is suspected to be a tumor suppressor but its exact role in cancer has not been elucidated.
2.)
3.) i. Determine nature of interaction with VHL.
ii. Examine mechanisms of cancer downregulation of trichoplein protein.
iii. Investigate transcriptional downregulation of trichoplein.
4.) MSc project is on the structural analysis of the HIF-1a - VHL interaction, via crystallization of the interaction complex containing the oxygen-dependent domain and associated functional studies.
2.)
3.) i. Determine nature of interaction with VHL.
ii. Examine mechanisms of cancer downregulation of trichoplein protein.
iii. Investigate transcriptional downregulation of trichoplein.
4.) MSc project is on the structural analysis of the HIF-1a - VHL interaction, via crystallization of the interaction complex containing the oxygen-dependent domain and associated functional studies.
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