I think Artificial Intelligence should be split up into a few different techs and spread out more over the ages.
Specifically, some tech something like this;
Basic Networks
Neural Networking
Malleable Programs
Self-updating Software
[Machine Senses]
[Advanced Gyroscopics]
True AI
[[Machine Rights]]
Those techs in [] are only relevant for certain machines, such as robots. [[]] Is a related social tech, one which I recommend allows a civic such as 'Mechanical Emancipation'.
Also note that Gyroscopics would be necessary for any form of mechs - indeed, that is the major current obstacle to building them today, as we possess much of the other required technologies.
Further technologies might include (To be included wherever they fit, I suppose.);
Zero-friction Materials (Would permit some incredibly efficient machinery.)
Unified Theory of Physics (Obvious benefits)
Dyson Spheres (Would make some massive changes to a civilization.)
Supermassive Construction (For the above)
Nanometric Construction (Also for the above, and pretty much everything else in a few decade's time)
Cybernetics (Better soldiers, tougher workers, possibly perfect loyalty/mind control)
Nano-optics (For both spying and stealth camo.)
Synergistic Martial Arts (A more sociobiological tech, possibly leading to a new civic or building. A dojo which increased health, for example.)
Brain Mapping (Mind control, a step against many diseases.)
Gene Splicing (Allows creation of new lifeforms.)
Genetic Manipulation (Allows many diseases to be eradicated, and characteristics to be decided.)
Post-Birth Genetic Modification (Allows people to change their gender, skin color, height, weight, hair, eyes, number of fingers, toes, arms, and legs, and much more besides.)
Organ Cloning (Might already be covered, but definately a boost for health.)
Biological Replication (Extends cloning and genome mapping to most/all known lifeforms.)
Environmental Undertanding (Allows weather control/large-scale controlled environments, leads to terraforming)
Subatomic Matter Manipulation (Alchemy, in a word.)
Unified Religious Theorum (Don't know how this impacts on in-game religions, I'd suggest this be more a philosophy-oriented tech, perhaps reducing the effect having similar/different religions has.)
Kardashev Scale Types I and II Civilizations
Alien Contact (Would probably be best more as an event like circumnavigating the globe...)
Theory of Sentience (A globally accepted ideal on what qualities are required for a being to be declared sentient. Possibly tied in with Machine Rights.)
Sentient Rights (Similar to Human Rights, but extended to any and all beings which fulfill or surpass the criterea decided upon in the previous tech.)
The Answer (I suppose this would be one of, if not the, ultimate techs. The Answer, simply...)