IMO this is a very balanced group, and all teams have a chance to qualify. If you only watch the roster, it should be clear that Italy is much stronger than the other 3 teams, with the Chech above USA and Ghana. But Italy is in bad shape and has some important injuries, like Zambrotta, Gattuso, Totti and Nesta. The last two could play the first game, but they're still recovering from injuries and won't play at their potential. Without one of the defenders, the most defensive midfielder, and the most talented player, suffering the absence of the only good right defender in the roster, Italy will likely have some serious defending issues, so I expect them to have a hard time in the group. Furthermore, they aren't probably concentrated enough, because of the mess there is in italian football at the moment.
Czech Republic has some great players, and did well in Portugal 2 years ago, but most of the stars are old: Nedved won't play at the levels of some years ago. I think this team is a bit overrated, overall. At the contrary, USA look fine and could be the surprise of the group and of the entire WC, because now they're quite experienced, some players are skillful, and they have less pressure. IMO they're going to the next round.
Ghana is a mystery, I think they have a stronger lineup than Czech Republic and USA, with most of the main players doing fine in the european leagues. They could be a serious challenge, but they may as well fail miserably, like many other African teams before. If they were in an easier group they could have a good chance to pass.
My guess:
1. Italy 5 pts.
2. USA 5 pts.
3. Czech Republic 4 pts.
4 Ghana 1 pt.