I feel as if I'm getting more comfortable on Emperor now. Latest attempt was a random civ (got Mongols), standard-size continents, epic, all default options. Fyi all my games are strictly no-reloading, ever.
As of 320 BC I rushed and took out Peter (axemen):

720 AD, took out Isabella (axemen):

Science is suffering and I'm rapidly burning through all the money I got from taking cities.
At this point Mansa Musa is having a field day taking out Montezuma on the eastern side of the continent. He's way ahead in tech, and still has a larger land mass than me. And I'm not even financial. He'll run away if left unchecked.
I must either cripple Mansa or get bigger myself. Mansa is currently #1 in military (despite my early focus on military all along) and much more advanced than me. I decide to go all the way and aim for Qin instead.
980 AD Qin's last dying breath (axemen, cats, elephants):

Near the end of my military campaign against Qin he got longbows which I didn't have. Doesn't matter, too little,too late.
Science is really plunging down and I wouldn't be able to research at all if not for the captured cities' plunder.
I shortly take out Qin, and finally my land size is #1. GNP is in dead last, and I'm quite behind in tech. I focus all my power to infrastructure from that point onward. As of 1145 AD:

18 cities strong and beginning to surge ahead.

That's all I've played thus far but I strongly suspect that the rest of the game will be academic. Mansa Musa is still up a few techs but they're stuff like theology and horseback riding, Education that I'm currently researching no one has yet. Victoria is on the other continent and I'm ahead of her in tech.
What I learned: don't be afraid to expand on higher difficulty settings, even if your science goes down to almost 0%. Generally speaking, land is power and the more you can afford to have, the better.
As of 320 BC I rushed and took out Peter (axemen):

720 AD, took out Isabella (axemen):

Science is suffering and I'm rapidly burning through all the money I got from taking cities.
At this point Mansa Musa is having a field day taking out Montezuma on the eastern side of the continent. He's way ahead in tech, and still has a larger land mass than me. And I'm not even financial. He'll run away if left unchecked.
I must either cripple Mansa or get bigger myself. Mansa is currently #1 in military (despite my early focus on military all along) and much more advanced than me. I decide to go all the way and aim for Qin instead.
980 AD Qin's last dying breath (axemen, cats, elephants):

Near the end of my military campaign against Qin he got longbows which I didn't have. Doesn't matter, too little,too late.
Science is really plunging down and I wouldn't be able to research at all if not for the captured cities' plunder.
I shortly take out Qin, and finally my land size is #1. GNP is in dead last, and I'm quite behind in tech. I focus all my power to infrastructure from that point onward. As of 1145 AD:

18 cities strong and beginning to surge ahead.

That's all I've played thus far but I strongly suspect that the rest of the game will be academic. Mansa Musa is still up a few techs but they're stuff like theology and horseback riding, Education that I'm currently researching no one has yet. Victoria is on the other continent and I'm ahead of her in tech.
What I learned: don't be afraid to expand on higher difficulty settings, even if your science goes down to almost 0%. Generally speaking, land is power and the more you can afford to have, the better.