On huge maps I notice that people tend to go with 8 civs which is the HOF limit. I was wondering if it is easier to play with fewer civs?
Yes, there are two different routes to take and the seem to get pretty close to the same results at the end....
Sir Pleb likes to play with 16, Aeson with 8. For the settler flood/ICS it is easier if you have only 8 civs (more goody huts, more time to set up the flood). However, with 8 civs the tech rate is slower, and you WANT it to slow down (as far as the AI researching). So you can swamp the AI with knights while they still don't have Iron hooked up. With 8 civs you have more room to expand, so you can claim more territory at the beginning of the game, and the AI spends more time also expanding, so it is building settlers instead of infrastructure. However, if you leave an AI civ alone it WILL become very large in size and seems like a difficult task to destroy them. Contact is much slower with 8 civs so that is one major reason for the tech slow down (India on my continent still has not met anyone but me, Aztecs and Iroquis have only met each other, Russia on the island has only met me and I'm researching Chivalry).
With 16 civs the tech rate is so much faster because contact amongst them is made so much faster, and they quickly trade all the techs amongst them. Fast tech rate helps in score, by getting you railroads and hospitals quicker. And each civ won't be all that big in size, so as long as you are much stronger, you can pick each one off one at a time easier. Also, there are 16 palace regions that have been developed (terrain improvements) to quickly establish those areas instead of improving them yourself.
Update: Culturally acquired Rome's Iron!
But now Greece got an Iron hooked up

. Good thing though is right now it's only connected to one city, so hopefully I can culturally acquire that one too. It's 320 A.D. and I have 7 luxuries, hoping to culturally acquire some incense from Russia, but that's going to be hard. I have about 50 horsemen ready to upgrade when I get Chivalry. Sun Tzu's due in another 10 turns or so. I think I have about 1200+points and gaining about 20 pts/turn.
With the new patch the power of the scout rescource denial doesn't have the power it used to (or has it always been this way?). I can leave scouts in AI territory, but if it is a square immediately adjacent to a city, I will be forced to leave. I can re-enter, but sometimes the AI gets a worker on the Iron first. Plus, since you can't simply just demand cities (you have to do the 0 turn war), if the scout was in AI territory at the moment you declared war, it kills your rep. So you can't sell ROP because even if you cancel the ROP, since you used the ROP to get your scout in AI territory it's considered a ROP abuse.