The only series of quests in Skyrim that I thought was really solid all the way through was the Dark Brotherhood. The Thieve's Guild was a mess, the Companions was boring, the College was absurd, the Civil War had a lot of potential but ended up being rushed and unsatisfying, the main quest had a few decent parts but ultimately leaned too much on "OMG DRAGONS!" as its only selling point. The DLC did better, I legitimately enjoyed both Dawnguard and Dragonborn, although the main villain in Dragonborn was pretty bleh. Overall it was a solid improvement over Oblivion, but that's not really saying much, and the writing was still far and away the weakest part of the game, just as it has been for all of Bethesda's games since Oblivion. If FO4 follows the recent pattern, I expect it to be fun and have a memorable atmosphere, but very few memorable characters or stories to tell. FO3's writing was probably the worst of any game they've ever released, I actually think the game would have improved by taking out all the dialogue and any pretense towards story and just making it an open world exploration game.