That looks like an interesting game. I am currently playing my first Prince level game and it is not too hard to beat, I think. I also played a financial leader and conquered my 2 closest rivals pretty early.
At that point, I had 12 cities and realized that even if I put research to 0%, I would have a small deficit!

Fortunately, I had over 300g at that point and could run research at 40% for a dozen turns. I already had lots of cottages and worked coast tiles to profit from the +1 commerce, but that was not enough. I had to build courthouses almost everywhere and go for calendar to have enough happiness to allow my cities to grow bigger than size 6 or 7 to support my expenses.
I don't know how the epic speed or the lake map will affect the game, but I bet I will run into the same kind of problem. I have never pop rushed anything in Civ4 yet, so lots of new things for me to experience! This is going to be fun!
As for the start, I think setting on the spot seems a good idea. Building a worker first seemed to help a lot in GOTM1, so I will do it again. BTW, I got 7 huts in GOTM1 which gave me 2 maps and 5 times gold, so hunting does not seem like a good idea. I will go for agriculture and/or animal husbandry to profit from the wheat and sheep as fast as possible. Considering the low hammer of London, I will probably keep the 2 forests in the plains, but will probably cut those on grassland for the first few settlers.
Without meditation as starting tech, we would have to go for Monotheism to get an early religion, so we are better to conquer one!
