I've had that experience in my first two games. In my first game, Ibn loved me the whole game because I was revealing the map, just like him. In my current game, Himiko seems to permanently hate me because of the buildings I have built (including my unique quarter). I do pursue relics in Modern, so Kathy also seems to permanently hate me. I am befriending more CS, so I am seeing more grumpy feelings.If you spend all your influence on befriending city states the civs will all hate you, but once I stopped doing that and spreading the love around it was easy to keep a friend or two.