Hearts, lungs, veins, ect...aren't built to last more than 100 years or so, and it all depends. It is pretty much impossible to stop the natural affects of aging, the reason the age of death has gone to higher ages is recent years, is, in part, because of much better health care, but unless you plan to start making cyberoptic and robotic parts for everything, there's a certain age that we all reach and then die, and that's pretty much not changable.