Actually, this whole business about the Ottomans and the Holy League brings to mind something I've been marinating on.
In a way, I kinda hope that Italy doesn't make it into BNW, because it would make for some rockin' DLC! Not just a civ, but an entire scenario based around Renaissance Italy with a focus on BNW's new trade and culture systems. Whaddya think?
The scenario is called "Most Serene Republic". You get to play one of Italy's major maritime republics: Venice, Genoa, Ragusa, or Florence. The Ottomans, Spain, and Holy Roman Empire would be AI civ's, with varying levels of established friendship or enmity at the beginning of the scenario, allowing certain republics to have an early edge on international trade routes.
With regards to city-states, most types are downplayed. Maritime, culture, and mercantile CS's are few or non-existent. Militaristic civ's, OTOH, should be around to provide vital manpower to help out the smaller republic with a limited production base, so Hungaria and Switzerland would be represented as military CS's, with their unique elite hussars and pikemen, resepctively. Not sure what to do with Rome and the Papal States; being understandably immune to DoW, they couldn't be playable, so it's either AI civ or CS.
The scenario starts in the Middle Ages, and finishes at the Industrial Era, perhaps with Napoleon showing up with beaucoup cannons to wrap things up with a bang.
Instead of great generals, the Italians have condottieri, drawing from history's long list of distinguished condottieri. Unlike most great persons, condottieri can be purchased with gold, and have a varied pool of abilities to from which to draw (a DIY master of tactics!).
Venice would probably have the strongest naval edge courtesy of its Arsenal. Florence, OTOH, would be the smallest and least militant, but with a big advantage in generating culture and great persons. Genoa would have a strong land army couresty of its crossbowmen and be better at acquiring condottieri. Ragusa could have a bonus trade route, or some other benefit relating to its Ottoman ties, or maybe a production benefit tied to forests.
Just throwing stuff out there. Feel free to toss some ideas into the mix.
The winner of the coveted "Most Serene Republic" title is the civ that either eliminates all rival republics, or completes the most objectives (in a manner similar to the Smokey Skies scenario). Objectives include amassing the most naval power, generating the most culture & tourism, and having the most lucrative trade routes.