Boris Gudenuf
Deity
Over 75% among Europeans on some of the Caribbean islands.Well, there is another benefitial point in being the one that reaches the “new” continent, actually: any disease lethal enough would kill at least half the ship crew before it reaches back to the old ports.
Yet mortality rates among settlers, specially those not used to hot caribbean climate were also not small.
This kind of mortality is why I would be very surprised to see a Pandemic/Epidemic mechanic in the game. As important historically as the effects were, the problem remains that they are the Angry Gods Event: there's absolutely nothing effective you can do about it until the last third or so of the second Age of the game. That makes for a game very dependent on 'random events' rather than astute (or less astute) gameplay, and a random event that wipes out 1/3 of your population, an then comes back a few turns later and wipes out another 20 - 30%, is simply not going to be acceptable to most players (although it would be Historically Accurate: the Antonine Plague, possibly Smallpox, hit the Roman Empire in 165 - 180 CE and the Plague of Cyprian, possibly Smallpox again or Influenza, hit in 249 - 262 CE: between them they caused major manpower shortage for both agriculture and the Roman army throughout the Empire)
Not the sort of thing in a game that makes the game design popular with the unsuspecting gaming public . . .