@Commander Bello
Would you please provide more info. i.e. Map size, Game Speed, .. etc. Your PC config. can also help. Also I understand that these CTDs are not repeatable i.e. When you reload the save file you can continue several turns forward (Am I right?).
The CvPath.py file is connected to the issue of losing interface. It has nothing to do with in-game CTDs.
I am testing a huge terra map - marathon speed. I am in the ADs now and I got no CTDs at all.
Sorry... the settings are so typically for me that I really forgot to mention them
Giant map, 10 civs at start, normal speed, RevDCM activated (of course

)
[remark: this makes for really interesting starts - you have enough space to expand, and the game becomes very dynamic in the ADs]
The CTDs are completely repeatable, in other words, the game crashes every time during the intra-turn.
My rig: Quadcore 2,4 GHz, 4 GB RAM, NVidia 8800 GTS (640 MB), Vista Ultimate 32bit, SP1, Swapfile 8,65 GB (own partition)
Except a Firefox, NAV, and the typical set of utilities (in this area, nothing has been added, so I am running the same configuration which under a RoM 2.01 environment did work smoothly up to the 1600's), only Civ4 is consuming computing power at ~35% in average.