Like Serg, I also use a lot of sessions, so I save and reload often.
In addition, I may reload if:
(1) I misclick or mi**** a key (I want the game to reflect my decisions, not my mastery of the keyboard);
(2) (if I have many cities) I may end the turn without checking for riots, for the sole reason to save RL time, then go back and adjust any rioting cities;
(3) I go back to an older save because I forgot to log something, to make an image, or to see what in the world happened to my Spice colony.
In none of these cases I gain any advantage from reloading.
I have no idea what my reload count is and what is considered 'too high', but I have no intention whatsoever to adjust the way I play the GOTM, which I consider 100% fair, let alone my life in order to qualify for the rankings.
Just like I have no intention to spill precious hours on milking, only because that gives a higher score. I know when I've played well and when not. If the rankings don't reflect that, so be it.
In addition to the above, it is actually very easy to cheat bigtime with a minimum of reloads. Just save 10 instances of the same decision moment under different names when you want that map knowledge, settler, flip, Great Leader, wonder or unique tech, and play 9 extensive try-outs for 1 reload. Don't turn off your computer until the game is finished and if you aren't too hopeless a player you can cheat your way to the top with say 5 reloads a game.