How does this prove that all mutations are harmful?perfect answer to your statement, mutations are adding up in the gene pool
I think one can make the argument that it was the apple eaten by Adam & Eve that cursed us with that.
Not that I'm making said argument.
Seems as if Court is in Session.
yes! please provide a mutation in humans that does not cause an information lost.Have you proven this yet?
answered in post above. evolution depends on "good" mutations but mutations are bad or neutral and natural selection can not remove them.Do you understand this thing called reproductive science? Phenotypes? Crossing Over? Cellular Reproduction? Gametes? Meiosis?
The only reason mutations are neutral because we dont know the full functionality of the genome. so they are labeled neutral because no apparent damage is found based on our knowledge. when mutations happen they are overwhelmingly bad or neutral not "good".This article does not disprove pizza's assertion that most mutations are neutral in effect.
sorry i meant to say that it was from the nature articlewhat does this mean?
please provide an example of an vestigial organ in humans. all organs have a functions in the bodyWhat about vestigial organs? We and other organisms are riddled with those purposeless things. Why?
How does this prove that all mutations are harmful?
please provide an example of an vestigial organ in humans. all organs have a functions in the body
Maybe not vestigial, but just as perplexing: male nipples
And wisdom teeth.
Here's two - the coccyx and the appendix.
perfect answer to your statement, mutations are adding up in the gene pool
http://www.newton.dep.anl.gov/askasci/mole00/mole00460.htm
At the red cell membrane, the Duffy antigen is the molecule used by the parasite P. vivax to enter the red cell. The high association of Duffy antigen null rell cells in some groups of people with sickle cell trait suggested that the Duffy antigen might provide some protection against malaria (Gelpi and King, 1976). Later investigations showed the Duffy antigen to be the receptor by which the merozoites of P. vivax enter red cells. People who lack the Duffy antigen (FY*O allele) are resistant to P. vivax (Hamblin and Di Rienzo, 2000). The Duffy null phenotype is most common in people whose ancestors derive from regions in Africa where vivax malaria is endemic.
Sickle hemoglobin provides the best example of a change in the hemoglobin molecule that impairs malaria growth and development. The initial hints of a relationship between the two came with the realization that the geographical distribution of the gene for hemoglobin S and the distribution of malaria in Africa virtually overlap. A further hint came with the observation that peoples indigenous to the highland regions of the continent did not display the high expression of the sickle hemoglobin gene like their lowland neighbors in the malaria belts. Malaria does not occur in the cooler, drier climates of the highlands in the tropical and subtropical regions of the world. Neither does the gene for sickle hemoglobin.
Sickle trait provides a survival advantage over people with normal hemoglobin in regions where malaria is endemic. Sickle cell trait provides neither absolute protection nor invulnerability to the disease. Rather, people (and particularly children) infected with P. falciparum are more likely to survive the acute illness if they have sickle cell trait. When these people with sickle cell trait procreate, both the gene for normal hemoglobin and that for sickle hemoglobin are transmitted into the next generation.
yes! please provide a mutation in humans that does not cause an information lost.
answered in post above. evolution depends on "good" mutations but mutations are bad or neutral and natural selection can not remove them.
The only reason mutations are neutral because we dont know the full functionality of the genome. so they are labeled neutral because no apparent damage is found based on our knowledge. when mutations happen they are overwhelmingly bad or neutral not "good".
genetic disorders are caused by mutations i listed them in my posting before. vestigial organs opinionated definition. if i cut off my pinky will i die? no. does that mean that my pinky is a vestigial organ. just because something has a small function does not mean it evolved over millions of years. my post was not about vestigial organs but how mutations(copying errors) do not fit the theory of evolution. mutations do not cause ape to man.Vermiform appendix, coccyx, tailbone, muscles in the ear, and Plica semilunaris of conjunctiva. Now where is my 15 negative mutations that fit the criteria I gave you early in this thread?
iirc sickle cell anemia actually has uses. I remember learning in a health class that SCA, which is more common among Africans, makes them more resistant to malaria or something like that, which would probably better explain why it is still persistent in the human genome.
I was right, and here's the proof:
source: http://sickle.bwh.harvard.edu/malaria_sickle.html
Sickle-cell anemia is a disease of red blood cells. Why would anyone call that a beneficial mutation? Well, in certain parts of Africa, the death rate from malaria is quite high. Malaria is caused by a tiny, one-celled organism that gets inside the red blood cells and eats up the hemoglobin. Now, that particular germ doesnt like sickle-cell hemoglobin. Carriers of one sickle-cell gene produce about half normal and half sickle-cell hemoglobin, and the malaria germ leaves them alone, too. So, carriers dont get malaria. But the cost is high: 25% of the children of carriers can die of sickle-cell anemia, and another 25% are subject to malaria. If you want to call that a good mutation, youre welcome to it! It seems doubtful to me that real improvement of human beings would result from accumulating that kind of beneficial mutant, and certainly hemoglobins ability to carry oxygen was not improved.
The gene for sickle-cell anemia has built up to high levels in certain African populations, not because it is beneficial in some abstract sense, but simply because the death rate from anemia in those areas is less than the death rate from malaria. Natural selection is a blind process that automatically accumulates genes for short-term survival, even if it reduces the long-term survival of the species. For that reason, evolutionists recognize that natural selection can occasionally lead to mischievous results detrimental to genetic quality. Thats the effect I think were seeing with sickle-cell anemia