How long does it take for the psychoactive effects of marijuana to wear off?
Because smoked THC is rapidly transferred into the blood stream, THC levels in the blood rise quickly immediately after inhalation. Depending on the dose, THC typically reaches peak concentrations of more than 100 ng/mL five to 10 minutes after inhalation and then rapidly decreases to between one and four ng/mL within three to four hours.
However, heavy marijuana users’ blood can contain detectable amounts of THC even after periods of abstention. In one controlled study, six of 25 participants tested positive for active levels of THC after a full seven days of abstention, with the highest concentration detected being three ng/ml of whole blood.4 In addition, the blood serum of heavy to moderate users may contain more than two ng/mL of THC at 24 or even 48 hours after smoking a single joint, a level that studies have shown does not produce impairment.5
This is a particular concern for medical marijuana patients who are using marijuana in compliance with state laws and their doctors' advice, but who would likely test positive for marijuana while sober. While the Colorado Legislature debated a per se THC limit of five ng/ml, Denver News’ medical marijuana reviewer (and medical marijuana patient), William Breathes, subjected himself to blood draws to test his THC levels. After a 15-hour period of abstinence, Mr. Breathes’ THC levels were still 13.5 ng/ml. According to his physician, Mr. Breathes was in “no way incapacitated” at the time.6 This first-person account demonstrates the very real possibility that medical marijuana patients and other heavy marijuana users could face criminal charges under a per se system even if they are not actually impaired.
The graphic below shows the mean plasma levels of THC and its metabolites (11-OH-THC and THCCOOH) for six subjects smoking a marijuana cigarette containing 34 mg of THC, following several days of abstinence (which would reflect an occasional user's pattern of usage).7
Additionally, several studies show that exposure to secondhand marijuana smoke (which could result from being in the same room with a person who is using marijuana) may cause a non-user to show THC concentrations in blood serum of several nanograms per milliliter.8
Does this mean that some DUID laws may actually criminalize sober drivers?
Yes, if they set a per se limit for THC. Furthermore, arresting and convicting motorists who only have marijuana metabolites in their systems (from having used marijuana days or weeks before) will certainly cause people who are completely sober to be arrested and wrongly convicted of driving under the influence of drugs.
The standard for scientists is to test blood and urine, but what about other bodily fluids, like saliva, or performance-based tests?
Because of the invasiveness of blood tests and the inadequacy of urine tests in determining impairment on the roadside (i.e., actual THC levels), police officials hope to institute roadside saliva testing in the near future. However, the technology for reliably testing saliva is still unavailable, and there are no national standards for testing saliva, as there are with blood and urine.
Significant work is being done to develop and implement modified field sobriety tests, which measure the behavior of drivers (reaction time, for example), rather than their bodily fluids.
MPP recommends a policy similar to most state laws on driving under the influence of alcohol: A driver who fails a roadside sobriety test should be required to submit to a blood test by a trained medical professional — or risk criminal and administrative sanctions. However, given the length of time after impairment THC can stay in a person’s system, no conviction for driving under the influence of marijuana should be based on a per se limit.