Science & Technology Quiz 2: The one with the catchy title.

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Geez, I'm totally blanking.

Mise and Perfection are being reminded of "dendrite" which is a component of a nerve cell (it receives the input from other neurons).
 
:) Not easily. I'm only working with the name here, and trying to figure out why it could be named "dendritic". I really should know this.
 
:hmm: I held back since I answered last time - but since no one seems to know:

dendritic cells are antigen-presenting cells present anywhere where exogenous pathogens could enter the body (mainly skin and lymph nodes) - they make sure that immune cells such as b-lymphocytes get to "see" invading pathogens. They can be detected e.g. by FACS analysis or immunohistochemistry by showing that they have MHC class II on their surface while being negative for for Fc-receptors II and III and the common B-cell marker B220. Now there probably is an easier way - but that is what we used to do in our lab ;)
 
It's been a while since I worked with DC, but I think CD68 and CD80 are useful. There's a lot of DC in the gut too.
Ori gets the next question.
 
It's been a while since I worked with DC, but I think CD68 and CD80 are useful. There's a lot of DC in the gut too.
Ori gets the next question.

CD68 (macrophage marker) and CD80 (B-cell marker) would do the same - exclude MHC class II bearing cells that are not dendritic cells :)

What is a cryoglobulin? - name one disease in which it can play role...
 
:p




yeah - but just a tad more specific would be nice ;)

i'm just going to spew out what i know, and you get to pick out what is right and what is complete nonsense. :)

i saw the 'globulin' in there, made the connection to protein, and that's as far as i can get with 100% surety of what i'm talking about. i don't know what cyro means. i'v e only heard of a 'cryovater' used on Kim Possible to flash freeze minicorndogs. (yeah, laugh at me if you want to) if it's not just some weird TV show, then i'd say cryo means to freeze.

the disease would have to be in either the muscle or blood plasma...can't think of any other places off the top of my head.

i've heard globulin associated with haemoglobin and immunoglobulin and that's it so far. and i've heard of fibrous proteins...but they don't have much to do with anything. globular proteins are partially soluble, if i remember correctly, which is why they make that sphere shape, the hydrophillic and hydrophobic reactions. freezing could affect that.

some immune type diseases: arthiritis, some hepatitises, some diabetes, and systemic lupus.

maybe the cryoglobulin freezes the joints and poof, arthiritis? i don't know. if i knew what cryo meant and wasn't going off of an animated TV show, i might be a little more successful and clear. then again, i don't know a whole lot about those diseases either. so i'm kind of at a loss either way.


Edit: I should have put some sort of warning before this, like: freshman college student that's only taken one advanced course in biology in high school and failed the exam at the end of the year.
 
I'm not allowed to answer this one, but I can assure you that cryo does indeed mean something to do with cold, and that globulins are proteins that might or might not be soluble.
Given that he's just answered something about immunology, would you say that your link to haemoglobin or immunoglobulin was more likely?
 
Is it a protein that is insoluble at temperatures X degrees higher than body temperature, so when you get a flu or something and your body temperature rises by more than X, the protein becomes insoluble and ineffectual, possibly worsening the situation?
 
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