There'S some decent historical justification for it, and the cultures are obviously different (but then Canada is a hodgepodge of different cultures anyway ; the myth of a Common Canadian English Culture is a bad joke independance fans like to tell themselves).
Politically and economically, it's likely to do at best as much harm as good. Regardless of what the latest Holy Dogma out of the Parti Québécois says about "effervescence".
(Yes, the whole Marois effervescence/turbulence inanity really turned me off the PQ and independance. You guys are either majorly delusional, take Québecers for idiots who won't realize on their own separation will be a painful thing no matter how it happens, or both)
For those not aware what the above paragraph is about, during the last leadership campaign in the Parti Québécois, one of the candidates, Pauline Marois, stated that there would be "turbulences" (ie, upheaval) in the event of separation. She was promply booed down by the rest of the party waving "reports" that said there would be no such thing, and eventually pretty much had no choice but to back down to "effervescence" ("excitement" - in a semi-negative sense - is the closest I can come up with).
As I said - either they're delusional, or they take Québecers for clueless morons. Either way, it was a majorly ridiculous move on their part.