COVID - A light on the horizon?

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Well we don't run an open air prison here, current measures are already stretching it, anyone who challenges them in court is likely to win - a "Full Lockdown" was never in the cards here...

Soon the curfew will have to go, so will the most severe travel restrictions I suspect.
 
Isolationist narrative? Isolationism has been one year of "lockdowns". The alternative was (and is) to make a real effort to surpess the virus and the lift most of the limitations imposed on socialization. And there is no indication that vaccines will help supress the virus anytime soon.
The means to do it are within reach and are simpler.

Wait... so you think we should sit and home and NOT use the only weapon we have right now? Because that will be faster?

errrmm....
 
It seems that the Eu won't be accepting any more AZ or J&J vaccines.
The local bozos here will have a hard time explaining why they keep using those, and pretending they have a plan.
 
If vaccines are a major part of the solution, where is that solution working? Israel? The UK? What in the fall of cases and deaths there is the result of vaccines and what is the result of lockdowns? The lockdowns have not ended there.

Well, here in the UK the lockdown was greatly eased, if not completely removed at the start of this week, so I guess we'll soon find out. Given how lax people had become about lockdown regulations even before that, it's dubious to attribute the decline in cases (and especially in serious cases seen in the hospitalisation stats) to that.

The incompetents cannot even keep the narrative straight. Now it's another of the hastily pushed vaccines suspended. If vaccines are the salvation how come they're stopped over "a few cases of clots"? If vaccines were tested and evaluated safe why is the story changing from one day to the next and countries simply copying the decisions others make?

The decisions over suspending vaccines are rooted in politics, not science. The scientific facts are not changing day to day - the verdict is there is an extremely rare cases a blood clotting side effect from the adenovirus based vaccines. Politicians are flailing around trying to figure out how to handle that, given that most of the general public is terrible at evaluating risk. People will be uneasy about a one in a million risk from a vaccine, while not even considering the risk from getting in a car and driving to get it. As for the vaccine testing and evaluation, the largest phase three trials were about 50,000 people. They were never going to pick up any effect so rare that it only shows up in less than 1 in 100,000 cases. That isn't from the vaccines being "hastily rushed" - no drug trial in history has been large enough to catch a side effect that rare. We could have had the longest, slowest and most detailed testing in history - and it still wouldn't have spotted any blood clotting issues until it went to full scale deployment.
 
Maybe we should use the chimp adenovirus vaccines only for those involved in monkey business?

I'll see myself out while you cringe...
 
They were never going to pick up any effect so rare that it only shows up in less than 1 in 100,000 cases. That isn't from the vaccines being "hastily rushed" - no drug trial in history has been large enough to catch a side effect that rare. We could have had the longest, slowest and most detailed testing in history - and it still wouldn't have spotted any blood clotting issues until it went to full scale deployment.

Thank you for making that point so clearly.
 
That sucks. Will you be offered an alternative? IIUC the severe JNJ cases are all female? Is it connected to contraceptives or estradiol?

The place I was going to only offered that option. I'm on the on call list today for Pfizer from the county, if someone doesnt show up, but no idea how many people are above me on the list.

There is the local hospital, there is the county health department that does various shots (Wednesdays Pfizer, last thursday they did another one, dont remember which one), and there is Walmart that was doing J&J.

Last week when I tried to get either one of the county appointments and they were all booked up (wife and stepdaughter got appointments set up a half hour earlier). When I checked the 6 walmarts within an hour drive, either they had none in stock or were all booked up. This week my local walmart had appointments and I got an appointment... until it was cancelled. We have a Walgreens, but from what I can tell, they dont have any, or the nearest Walgreens that does is 3 hours away. Could be Walgreens doesnt post this stuff on internet and I'd have to call them, but really, I dont want to play this game of hunting for the vaccine.
 
Yup. None available through May around here. And since we're making such good progress with the old plan under the right color they opened up the dosing to the young. Yup, not getting one. Either they're so stupid on math that the CDC and FDA can't be trusted to operate a fork, much less an approval study, or they're lying about why its suspended. Or, Isuppose, the most likely. The small amount of liability thier buddies get from one in a million blood clots is more important than actual vaccination to them. Either way, they can all go burn in hell.
 
More on "it is better for everyone if everyone gets vaccinated":

Lancet infectious diseases:

An Editorial earlier this year described the potential for the evolution of SARS-CoV-2 variants that render vaccines less effective (vaccine escape). The vaccine escape risk is sensitive to background incidence; the risk of an escape variant appearing within a fixed time is an increasing function of incidence (figure). Reducing cases is not only beneficial for decreasing the pressure on health-care systems, but also for lowering the vaccine escape risk.
gr1_lrg.jpg


Spoiler Current number of daily cases? :
~ 4 million? So it is certain to happen?
novel-coronavirus-cases-worldwide-2021-week-13.png
 
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Denmark just decide to stop using astrazeneca entirely. This is just dejecting. This abundance of caution of theirs is going get a lot of people killed.
 
368 official dead today. The government continues to blame deaths on the opposition.

Almost exactly an hour ago the so-called president announced a new curfew that will be enforced using all forces available, including the army. ‘Non-essential’ activities such as school and working are forbidden. This was publicised through a pre-recorded broadcast. It is blatantly unconstitutional, a a betrayal of statements made only this morning, and also a betrayal of all the promises made during a similar broadcast only six days ago last week.

Almost immediately people started demonstrating from the windows and balconies of their prison-homes. I'm honestly not sure whether I'll bother to actually ‘respect’ it this time around.

It also comes with a side dish of statements that freedom of the press could/should be curtailed to further ‘the public good’. :ack:

Edit: over three and a half hours after the speech, localised street protests are still going on.
 
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As things go…
Mexico’s high Covid death toll blamed on populist government
New report points finger at nation’s penny-pinching policies and failure to act on scientific advice

Mexico’s unwillingness to spend money, do more testing, change course or react to new scientific evidence contributed to the country being one of the worst-hit by the coronavirus pandemic, a report has concluded.

Spoiler :
Mexico would have had a significantly lower death toll if it had reacted as satisfactorily as the average government, according to the Institute for Global Health Sciences, at the University of California, San Francisco, which also released a report sharply critical of the US response to Covid-19.

Mexico’s health department officially says there have been almost 210,000 deaths in the country of 126 million, but because so little testing has been done, Mexico acknowledges that the real toll is nearer 330,000. The US and Brazil have higher tolls, but also much larger populations.

The failures by officials to recommend face masks, bring in travel restrictions, provide enough testing and protective equipment and introduce social distancing measures were among the mistakes cited by the report, commissioned by the World Health Organization’s Independent Panel to the Institute for Global Health.

“Key decisions about how to confront the health crisis were based on unwarranted assumptions, without sufficient evaluation and judgment of the risks,” according to the report.

It cited excessive concentration of authority and “a government communication campaign that prioritised keeping up appearances, and partisan politics, before health”.

Hugo López Gatell, the assistant health secretary, who acted as the government’s point-man in the pandemic, repeatedly said that wearing face masks did not protect people, even after evidence mounted to the contrary.

“It is no coincidence that countries with the worst performance in responding to the Covid-19 pandemic have populist leaders,” the report said.

“They have in common traits such as minimising the severity of the condition, discouraging the use of face masks, prioritising the economy over saving lives, and refusing to come together with political opponents to mount a coherent response.”

Neither López-Gatell nor the government has commented on the report.

Austerity-minded President Andrés Manuel López Obrador has spoken with pride of not acquiring debt during the pandemic and not launching economic stimulus programmes.

But the report says that penny-pinching may have played a role in decisions not to expand testing, trace cases and quickly acquire PPE.

“From the outset, health authorities deemed efforts to stop or contain the virus futile and a waste of scarce resources, arguing instead for a mitigation approach and the preparation of the health system to care for the small minority that would require medical attention,” the report said.

The human cost of the missteps has been overwhelming. “Every day I cry for my son, for the circumstances” in which he died, said Martha Méndez Guevara, whose son, TV sports journalist José “Pepe” Roldán Méndez, 43, died of Covid in June.

Méndez Guevara said she could not judge if authorities’ response to the pandemic was sufficient, in part because she never got to see her son after he was admitted to a government hospital in May. “We don’t know if they did enough for him – because we we were not allowed to visit him.”

The report noted that López Obrador’s administration had to contend with an already overstretched health care system and citizens’ “delays in seeking medical care out of fear that once admitted to a hospital, people would contract the disease or die”.

This meant many patients arrived at hospitals in advanced stages of the disease.

“The high prevalence of chronic diseases, in combination with suboptimal timeliness and quality of medical attention, have likely contributed to relatively high Covid-19 mortality among the non-elderly population in Mexico,” the report said, referring to Mexico’s very high levels of obesity and diabetes.

That also led to greater mortality among younger patients; 50.6% of all Covid-19 deaths in Mexico occurred among people aged under 65, compared with 18.7% in the US.
tl;dr López Obrador, like Bolsonaro, sucked up to Trump in both speech (he said that the US was treating Mexico with respect) and practice (discouraged using facemasks, denied basic science, rebuffed opponents) and now you see the price.
 
The OAZ vaccine really is the Oxford Vaccine, with 3% input for AstraZeneca:

Oxford/AstraZeneca Covid vaccine research ‘was 97% publicly funded’

At least 97% of the funding for the development of the Oxford/AstraZeneca Covid-19 vaccine has been identified as coming from taxpayers or charitable trusts, according to the first attempt to reconstruct who paid for the decades of research that led to the lifesaving formulation.
Using two different methods of inquiry, researchers were able to identify the source of hundreds of millions of pounds of research grants from the year 2000 onwards for published work on what would eventually become the novel technology that underpins the jab, as well as funding for the final product.
The overwhelming majority of the money, especially in the early stages of the research, came from UK government departments, British and American scientific institutes, the European commission and charities including the Wellcome Trust.

Less than 2% of the identified funding came from private industry, the researchers said, a finding they said posed a challenge to the views of people such as Boris Johnson, who has said that the record-fast development of Covid-19 vaccines was “because of capitalism, because of greed”.
Johnson made the remark privately, but the same message has been promoted by the pharmaceutical industry, which has warned against waiving patents for Covid-19 vaccines – and other measures that could widen access – by arguing that ownership rights and the ability to generate profits are a key driver of vaccine innovation.
“Our study shows that quite the opposite is true: public investment and international collaboration gave us the Covid-19 vaccines,” the team of researchers, from the advocacy group Universities Allied for Essential Medicines UK, said in a statement.
And a load of leaders think we should not enforce IP on the vaccines:

More than 170 former world leaders and Nobel laureates say waiver is key to ramp up global vaccine production.

A group of more than 170 former world leaders and Nobel laureates is calling on United States President Joe Biden to make COVID-19 vaccines more readily available by waiving US intellectual property rules.
In an open letter shared by Oxfam on Wednesday, the signatories also urged Biden to support a proposal spearheaded by South Africa and India demanding the World Trade Organization (WTO) temporarily waive COVID-19 vaccine patents.

The measure would allow vaccine manufacturing to ramp up globally, the letter reads, as public health experts have raised concerns that low-income countries are behind left behind without access to critical coronavirus jabs.
At the current rate, the world’s poorest nations will have to wait until at least 2024 to reach “mass immunisation”, the signatories, which included former UK Prime Minister Gordon Brown, ex-French President François Hollande and Muhammad Yunus, winner of the Nobel Peace Prize, said.
“We believe this would be an unparalleled opportunity for the US to exercise solidarity, cooperation and renewed leadership,” they said.​
 
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https://www.euronews.com/2021/04/07...-brain-disorders-within-six-months-says-study
A third of COVID-19 patients suffer brain disorders within six months, says study
[...]
Of the 236,000 people surveyed, 34% received a positive diagnosis of neurological or psychiatric disorders within six months of their COVID-19 diagnosis. A total of 13% of these had received the diagnosis for the first time.

For those who had been hospitalised with COVID-19, the figure was much higher: 46% of which 26% had received the diagnosis for the first time.

This sounds ... too much to me. if it's real, then this is pretty bad.
 
The "Sexiest Man Alive" (?) has an interesting and short bit on the vaccine, that ends:

The speed and efficiency with which these highly efficacious vaccines were developed and their potential for saving millions of lives are due to an extraordinary multidisciplinary effort involving basic, preclinical, and clinical science that had been under way—out of the spotlight—for decades before the unfolding of the COVID-19 pandemic. When the stories and recounting of this pandemic are written, it is important that this history not be forgotten, as we are reminded once again of the societal value of a sustained and robust support of our scientific enterprise.​
 
The "Sexiest Man Alive" (?) has an interesting and short bit on the vaccine, that ends:

The speed and efficiency with which these highly efficacious vaccines were developed and their potential for saving millions of lives are due to an extraordinary multidisciplinary effort involving basic, preclinical, and clinical science that had been under way—out of the spotlight—for decades before the unfolding of the COVID-19 pandemic. When the stories and recounting of this pandemic are written, it is important that this history not be forgotten, as we are reminded once again of the societal value of a sustained and robust support of our scientific enterprise.​

Maybe "sexiest man alive born before the franco-prussian war" :)
 
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