I know the V 38.5 guide states that their are too many complicated factors involved in crime and disease to consider when playing, but I often find these values keep going up even as I make measures to lower them. I'm not looking for specific details, just the general factors (e.g the higher factor x, the higher crime is; the lower factor y, the higher disease).
Also, I've noticed that after building a wonder (I forget the name) that provides -100 disease/turn, the city was at -100/turn, then quickly dropped to -80/turn the next turn, eventually reaching zero. Does the rate of disease (and crime, I guess) increase/decrease with respect to the current number for disease? Like, should I worry about, say, +2 disease/turn if I'm at -300 disease?