So one major problem we had in Civ4 RoM was the cramped tech tree for anyone who wanted to add to it. The early eras had like 4 or 5 columns and 10 rows. I think first each era should save space for 10 columns and 10 rows. This spreads out the tree but gives lots of room if we add additional techs (max 100 techs per era). In addition if the prehistoric era is not in the official Civ5 RoM then please leave 10 columns at the beginning as a buffer so other modders can add to it.
I think we will have many more techs than before if we have the whole golden age era techs, thus there will need to be room for them. I also noticed that the trans-human age had the most techs of all the ages. This should be fixed with Civ Fuehrer's space themed mod called "The Ascent of Mankind". See
his thread about how it fits in.
In short as long as RoM either includes OR works together to make space with these other mods then we should not have any conflict. I mean really how cool would it be to go from a prehistoric nomad wandering around to following alternative tech paths to having colonies on other planets? I can't wait for this to become a reality! Civ5 RoM will be even more amazing than civ4 if we can pull that off.