Played 10 turns of a new game as Rome on emperor/fractal/standard. Here's what I noticed.
1) Started next to China, he proceeds to give me a free 2nd city with an unescorted settler...
This only happens with the bonus settlers given to the AI on higher difficulties.
2) The border expansion info covers up the tile too much, it also changed to a different tile mid way through expanding...
3) Ghandi whom I hadn't met is unhappy I DoW China. ( the turn after I met him he told me this )
4) Turning off auto unit cycle makes me click unit has orders each turn when I just have the starting warrior. Nothings selected initially each turn.
5) My starting location had no luxuries of any kind in its radius, which is a first for me in 250 hours.
When I start a new game in DX12 It didn't center on my settler and warrior but at the edge of my screen( most of my screen is fog ) also noticed what seemed like worse performance so I went back to the default.