Heheh, well I was just brainstorming, but actually I left out the craziest ideas. Let's add them back in to get things really stirred up.
- Add or remove extra AI civs.
- Turn a peninsula into an island or vice versa (but not the player's starting landmass).
- Disallow certain VCs altogether, e.g. diplo on hard levels, conquest on pangaea maps.
- A later start date!

The predator save is from e.g. 3500bc, and the starting units have been idling for 10 turns.
- Play with three traits (for conquest class on high level games).
- No UUs (but where's the fun in that?)
So these ones aren't really serious, but as for the previous bunch:
I don't think there is anything wrong with a handicap which postpones a predator player's victory. I think many of our existing handicaps do that, and it isn't always rational to chose predator. In GOTM50 I was beaten to my VC by an open player, but I'm not bitter (well, I couldn't have beaten him anyway

)
I don't see why making minor amendments to the map makes games
less comparable than other bonuses/handicaps. In the Dutch COTM, the predator handicap was loss of the agricultural trait: very harsh, and it made the opening plays of different classes almost totally incomparable.