I'm also having some funny problems.
Although I've added my own mod under modules that adds a civ, and gives some extra UUs, i haven't experienced anything like this before. I started a game in, i think patch E. Then i upgraded to F. No problems. I then skipped G, and got H when it came out. Now my game is broken, sort of. It crashes on 'initializing' when i try to load, BUT, if i load an old save from the same game, on about turn 100 or so (my game is at about turn 400+ now) it will load. Now it gets stranger: if i exit to menu after loading the old save, and then try to load my most recent save, it loads! But even after playing for a bit on that save, with patch H now installed, i still have to do the same process every time i play, or else it'll crash on 'initializing'.