I actually would have won in 1545 if I had bothered to found Tiflis earlier, but I still like dawdling sometimes. Oh well.
First turn, moved the inhabitants of formerly Babylonian Gordion across the Bosporus and founded Istanbul. Babylonia was massive, with Hattusas (Bogaskoy), Sur, Artacoana, Ninovah, and Artashat. They also happened to have around ten wonders. Astashat (on the Caspian) had Moai and Great Lighthouse! Even Sur had the ToA. I gained a lot of goodies. Germany had just captured Athen.
Germany, Ethiopia (w/ AP), and Babylon were Jewish. Persia and Russia were Buddhist. Spain was the only Christian nation (the Holy City Sparte had been destroyed earlier.) Everyone else was Muslim (India switched from Hindu to Buddhist at some point).
Babylonia declared war, then collapsed. There was empty space between Athen and the next German city, Klagenfurt, so I founded Dirac in Croatia. Then I built Yas in Moldova, and whipped out a settler in Istanbul when it grew to size 6 (pretty quickly). Taganrog was founded just before German and Russian settlers got to the area. Tiflis I left for later, but I wasn't expecting three vassals so quickly.
I gained 9 GP, seven of them Scientists from Bogaskoy (Great Library and two other Wonders), two Merchants from Istanbul to settle there and build Wall Street. Many Academies were built around the empire with the scientists. This helped me stay way ahead in the race for techs.
I took Babil, the Persians gifted me Ninovah, and I had an uneasy peace between them and the Arabs the whole game. All of my wars involved Europe.
Portugal, Mali and Netherlands all decided they wanted to be my vassals early on. I didn't even have to ask.
I saved the 1610 because that was when Tiflis was founded (and Atina captured). As I played on I got France to voluntarily vassalize, and almost lost Netherlands and Portugal at various times, so I chose to keep playing to legitimize the virtual UHV. At one point early, the Dutch were down to two badly wounded units in Amsterdam when I made peace with the Germans; the Portuguese lost Lisboa to the Spanish, but managed to hold on, even after Arguim declared independence. Both of these incidents happened post-Eyelat of France, so I still would have had three other vassals, but still...
Spain, Russia, and Germany were my nemeses. I was always at war with one or two of them throughout. I actually lost 100 points (over 200 normalized) due to a plague that knocked off five points of pop, on average, from
each of my cities during the five turns prior to victory.

Did stay Solid/Very Solid throughout, except for the last couple turns (thanks to the plague).
Interesting to note: Built the SoL in Dirac (Europe). Evidently, Istanbul is not considered a part of Europe, but Tiflis (the desert just south of the Caucasus on the Black Sea) is.
Lefkosa is the same spot as Knossos would be for Greece, so the island south of Athens can be Crete when Greece builds on it, or Cyprus when Turkey does. Interesting mix, Rhye.
Too bad I couldn't build anything but work boats in Artashat (the Caspian is off-limits for warships). With the wonders, I would have loved to attack Russia with some amphibious units.
Attached is the 1610 save and the screenshot from 1872 (I keep forgetting to capture a screenshot before continuing).