• Civilization 7 has been announced. For more info please check the forum here .
A solar storm will be causing a super-charged Aurora Borealis over the Northern Hemisphere tonight. The NOAA estimates that virtually all of Canada and slivers of the United States, Russia, and Northwestern Europe have close to a 100% chance of seeing it (weather permitting? can you see the aurora through clouds?).


 
Neanderthal–human baby-making was recent — and brief

Mixing between Neanderthals and Homo sapiens lasted less than 7,000 years — a remarkably short time considering that almost every living individual not of African ancestry carries a substantial amount of Neanderthal DNA. Researchers compared the genomes of individuals who lived between 2,200 and 45,000 years ago with those of modern people and found that the genetic intermingling started around 47,000 years ago. It ended around the time when Neanderthals went extinct.

This large-scale, multi-millennia-spanning comparison made it more straightforward to monitor ‘introgression’ of Neanderthal-derived sequences into the modern human genome. The results indicated that Neanderthal-derived genetic contributions in the modern samples could be traced to a single ‘pulse’ of gene flow starting roughly 47,000 years ago — more recently than originally projected —and spanning some 6,800 years, ending around the same time that Neanderthals were nearing extinction. Nearly 7,000 years might seem like a long time, but it is remarkably short on evolutionary timescales considering the sizable changes that the human genome underwent.

Notably, many of the Neanderthals’ genomic contributions were subsequently removed with remarkable speed from the H. sapiens genome. Modern human genomes contain vast ‘deserts’ that have been fully cleared of Neanderthal remnants — but the authors detected these deserts even in ancient genomes from the latest stages of human–Neanderthal interaction. According to Emilia Huerta-Sanchez, an evolutionary biologist at Brown University in Providence, Rhode Island, this suggests that many Neanderthal sequences could have been detrimental to humans, and were therefore actively and rapidly selected against by evolution.
 
Or killed off. I can't remember where modern science sits on the relations between Neanderthals and home sapiens. I know we've investigated the violence angle a bit and the conclusion hasn't always been the same.
On an individual level both certainly happened.
 

Scientists tested replica Bronze Age armour on Greek marines. Here's what they learned​

Despite its bulky appearance, the copper plate armour proved versatile and practical in combat simulations

learned
More than a dozen elite Greek marines dressed up like Bronze Age warriors and practised ancient fighting techniques — all in the name of science.

The 13 soldiers, all members of the Hellenic Armed Forces, roleplayed as warriors from Greece's late Bronze Age, known as the Mycenaean civilization, in order to test the combat suitability of a 3,500-year-old suit of armour.

The study, published last week in the journal PLOS One, is being hailed by some experts for its innovative approach of mixing physiology, the study of how the human body works, with archeology, the study of ancient materials and remains.

But they also questioned the historical accuracy of the simulated combat, and cautioned against using this one suit of armour to draw broad conclusions about the Mycenaeans — people whose cultures and societies remain something of a mystery.

Recreating ancient conditions

At the heart of the study is a suit of Mycenaean armour discovered in the southern Greek village of Dendra in 1960.

Made of copper alloy plating tied together with leather, and featuring a boar-tusk helmet, it is one of the oldest complete suits of European armour in existence.

But, given its weight and bulk, there's long been debate about its purpose.

"The main question was: Was that particular armour for ceremonial purposes, or was it also a battle tool?" University of Thessaly physiologist Yiannis Koutedakis, one of the study's authors, told As It Happens host Nil Köksal.

"The verdict was that it could be used for both."

To reach that conclusion, Koutedakis and his colleagues created a replica of the Dendra armour, then tested it on modern soldiers during a gruelling, 11-hour simulation of late Bronze Age combat.

Using descriptions of the legendary Trojan War from Homer's Iliad as a guide, the soldiers fought, tossed javelins, ran on treadmills and carried out various combat movements. Throughout, scientists monitored their blood sugar, heart rates, oxygen intake, core temperatures and more.

The team also tried to mimic Bronze Age battle conditions by recruiting male volunteers of roughly the same age as ancient Greek soldiers, controlling the temperature of the room where they performed combat simulations, and feeding the participants a traditional diet of meats, dry bread, goat cheese, olives and red wine. No coffee was allowed.

"We measured the physical … impact that this armour had on the individuals, and we noticed that it was fine, not something extreme," Koutedakis said. "It was heavy, but not too heavy. Not unbearable."

The findings back up earlier research by archaeologist Barry Molloy who, in a 2013 analysis, concluded the Dendra armour was fit for extensive combat.

Molloy was unavailable for comment, but he told National Geographic: "Suits of armour like this would have transformed the battlefield."

Who were the Mycenaeans?

The study's authors write that their findings "support the notion that the Mycenaeans had such a powerful impact in Eastern Mediterranean [society,] at least partly as a result of their armour technology."

But Dimitri Nakassis, an archeologist at the University of Colorado Boulder who specializes Mycenaean societies, cautioned that there's a lot we don't know about this period — including whether the Mycenaeans were really the fierce warrior culture they were reputed to be.

"I think most archaeologists would recognize [Mycenaean is] kind of a shorthand," Nakassis, who wasn't involved in the study, told CBC.

"We don't know who these people were. We don't know what they called themselves. We don't know that they had a kind of unified identity."

In order to be certain this style of armour gave Mycenaeans an advantage on the battlefield, he says more evidence that it was in wide usage is needed.

What's more, he says similar experiments are needed on other sets of armour from the same period.

"They suggest ... maybe this gave the Mycenaeans an edge, and I think that's a possibility that we should take seriously," Nakassis said. "But, obviously, it requires more research."

Historical inaccuracies

There were also limitations on the researchers' ability to perfectly replicate Bronze Age combat in a historically accurate way.

Ioannis Georganas, an independent archeologist and member of the Society of Ancient Military Historians, noted that while Dendra armour was 90 per cent copper and 10 per cent tin, the replica was 95 per cent copper and five per cent zinc.

What's more, he said, in an email to CBC, basing the combat simulations on Homer's epic poetry is "more than problematic."

Scholars have long debated what's fact and what's fiction in Homer's tales. The Trojan War was set centuries after the Dendra armour was created, and some 500 years before Homer was even born.

In the study, the researchers acknowledged both of these shortcomings, noting they used the closest approximation of metals, and the most accurate descriptions of Bronze Age combat that they could get their hands on.

They say these discrepancies don't call into question their key finding — that the Dendra armour is practical, versatile, and combat ready.

Despite their caveats, both Georganas and Nakassis said they welcomed the study's unique approach to blending physiology with archeology, and said they hope to see more research like it.

Koutedakis agrees.

"We have now coined a new term — archeo-physiology," he said. "And I hope that ... other projects may be done in a similar way, and that will be very good."

Asked if he had a chance to try on the replica armour himself, Koutedakis immediately replied: "Of course I did!"

"To have something on your body, which you knew that people were wearing 3,500 years ago," he said, "that feeling is really amazing."
https://www.cbc.ca/radio/asithappens/greek-bronze-age-armour-study-1.7217371
 
Japan’s push to make all research open access is taking shape
Japan will start allocating the ¥10 billion it promised to spend on institutional repositories to make the nation’s science free to read.

The Japanese government is pushing ahead with a plan to make Japan’s publicly funded research output free to read. In June, the science ministry will assign funding to universities to build the infrastructure needed to make research papers free to read on a national scale. The move follows the ministry’s announcement in February that researchers who receive government funding will be required to make their papers freely available to read on the institutional repositories from January 2025.

The Japanese plan “is expected to enhance the long-term traceability of research information, facilitate secondary research and promote collaboration”, says Kazuki Ide, a health-sciences and public-policy scholar at Osaka University in Suita, Japan, who has written about open access in Japan.

The nation is one of the first Asian countries to make notable advances towards making more research open access (OA) and among the first countries in the world to forge a nationwide plan for OA.

More at...
 
Puny humans!

Scientists Find the Largest Known Genome Inside a Small Plant

Last year, Jaume Pellicer led a team of fellow scientists into a forest on Grande Terre, an island east of Australia. They were in search of a fern called Tmesipteris oblanceolata. Standing just a few inches tall, it was not easy to find on the forest floor. "It doesn't catch the eye," said Dr. Pellicer, who works at the Botanical Institute of Barcelona in Spain. "You would probably step on it and not even realize it." The scientists eventually managed to spot the nondescript fern. When Dr. Pellicer and his colleagues studied it in the lab, they discovered it held an extraordinary secret. Tmesipteris oblanceolata has the largest known genome on Earth. As the researchers described in a study published on Friday, the fern's cells contain more than 50 times as much DNA as ours do. [The analysis revealed the species T. oblanceolata to have a record-breaking genome size of 160.45 Gbp, which is about 7% larger than that of P. japonica (148.89 Gbp). For comparison, the human genome contains about 3.1 Gbp distributed across 23 chromosomes and when stretched out like a ball of yarn, the length of DNA in each cell only measures about 2m.

A 160 Gbp fork fern genome shatters size record for eukaryotes
 
Does anyone have access to this article fron New Scientist?

A new theoretical model suggests time may only exist due to entanglement between quantum objects.

What is time?
Time may not be a fundamental element of our physical reality. New calculations add credence to the idea that it emerges from quantum entanglement, in which two objects are so inextricably linked that disturbing one disrupts the other, no matter how distant they are. Alessandro Coppo at the National Research Council of Italy and his colleagues put a promising but strange idea from the 1980s through several mathematical tests. At its core is the suggestion that when we see an object change over time, that is only because that object is entangled with a clock. That means a truly external observer standing outside the entangled system would see a completely static, unchanging universe. Within this framework time is not a given, but purely a consequence of entanglement
 
Does anyone have access to this article fron New Scientist?

A new theoretical model suggests time may only exist due to entanglement between quantum objects.

What is time?
Time may not be a fundamental element of our physical reality. New calculations add credence to the idea that it emerges from quantum entanglement, in which two objects are so inextricably linked that disturbing one disrupts the other, no matter how distant they are. Alessandro Coppo at the National Research Council of Italy and his colleagues put a promising but strange idea from the 1980s through several mathematical tests. At its core is the suggestion that when we see an object change over time, that is only because that object is entangled with a clock. That means a truly external observer standing outside the entangled system would see a completely static, unchanging universe. Within this framework time is not a given, but purely a consequence of entanglement
There is this.
 
I have to point out at the start that odd apparent correlations in data that are not really there when the data is looked at holistically is a real thing and explains a lot of things. It also has to be pointed out that this is not the first time one of these people has been making such claims, a point made but not explored in the article. On the other hand "the man" has got form about lying about this sort of thing.

Top Canadian scientist alleges in leaked emails he was barred from studying mystery brain illness

A leading federal scientist in Canada has alleged he was barred from investigating a mystery brain illness in the province of New Brunswick and said he fears more than 200 people affected by the condition are experiencing unexplained neurological decline.

“All I will say is that my scientific opinion is that there is something real going on in [New Brunswick] that absolutely cannot be explained by the bias or personal agenda of an individual neurologist,” wrote Michael Coulthart, a prominent microbiologist. “A few cases might be best explained by the latter, but there are just too many (now over 200).”

New Brunswick health officials warned in 2021 that more than 40 residents were suffering from a possible unknown neurological syndrome, with symptoms similar to those of the degenerative brain disorder Creutzfeldt-Jakob disease. Those symptoms were varied and dramatic: some patients started drooling and others felt as though bugs were crawling on their skin.

Spoiler Last time :

1990: Gummer enlists daughter in BSE fight

The government has again attempted to reassure the public that British beef is safe, despite growing fears over the cattle disease, Bovine Spongiform Encephalopathy (BSE).

The Minister of Agriculture, John Gummer, even invited newspapers and camera crews to photograph him trying to feed a beefburger to his four-year-old daughter, Cordelia, at an event in his Suffolk constituency.

Although his daughter refused the burger, he took a large bite himself, saying it was "absolutely delicious".
 
MDMA therapy for PTSD rejected by FDA panel

I do not actually know anything about it, but considering the evidence that got lecanemab approved I suspect this is more to do with its image than the strength of science.

In a decision that shocked some observers, key advisers to the US Food and Drug Administration (FDA) voted that the effectiveness of the party drug MDMA for treating post-traumatic stress disorder is unproven.

Members of an independent scientific advisory committee voted 9 to 2 that human trials of MDMA did not prove its efficacy. They also voted 10 to 1 that the risks of MDMA, also known as ecstasy, outweigh its benefits. The FDA does not have to follow its advisory committee’s recommendations when deciding whether to approve a drug, but often does.

The vote highlighted the difficulty of assessing psychedelic drugs and the FDA’s limited ability to evaluate psychiatric treatments. “It felt strange to vote no,” says committee member and statistician Satish Iyengar at the University of Pittsburgh in Pennsylvania, given that the drug’s effects seemed so strong. “There were just too many problems with it.”

The meeting was held 4 June in Silver Spring, Maryland.

Long campaign

MDMA is a synthetic compound that can evoke euphoria and raise energy levels. It has already been approved for limited use in Australia to treat post-traumatic stress disorder (PTSD) and depression.

For decades, the nonprofit group Multidisciplinary Association for Psychedelic Studies (MAPS) in San Jose, California, has been running MDMA clinical trials and campaigning for drug legalization worldwide. The association’s commercial arm, Lykos Therapeutics in San Jose, has developed an MDMA treatment protocol involving a series of psychotherapy sessions, along with three sessions in which a team of two therapists administers MDMA. The idea, the company has said, is that MDMA is not a treatment in itself, but rather helps people open up to their therapists about traumatic events that might otherwise be difficult to confront.

In its application to the FDA, Lykos cited two clinical trials1,2 in which a total of around 200 people with PTSD received either MDMA or a placebo. More than 80% of those who received MDMA saw significant improvements in their symptoms. And the effect seemed to persist when investigators followed up with a portion of these participants between 6 and 24 months later.

Lingering concerns

But FDA scientists themselves had a number of concerns about Lykos’s studies, which they felt were lacking crucial psychological and physiological safety data. A major concern was the fact that participants — and their therapists — could almost always tell whether they had received MDMA or a placebo. An FDA report released ahead of the meeting called the data “challenging to interpret”.

“The fact is you just can’t blind these studies,” FDA psychiatry division director Tiffany Farchione said at the meeting. In 2016, MAPS and the FDA agreed on a protocol in which an independent assessor who had not taken part in the trial would evaluate each person’s psychiatric progress. But both FDA staff and the advisory committee remained worried that people’s expectations of receiving a drug would affect their response to it.

Other concerns included the fact that around 40% of the trial participants had taken illicit MDMA before the trial, potentially biasing the sample. And many sought other treatments — including psychedelic drugs — between the initial trial and the follow-up, suggesting that their symptoms might have continued and that their improvement might not have been due entirely to MDMA.

Many of the advisory committee members’ questions centered on the role of psychotherapy. Lykos has developed a therapy protocol that would be administered along with the drug. But the FDA does not regulate therapy. The most it can do is ensure that medical practitioners overseeing the drug’s administration provide some therapy.

Therapeutic wild card

Lykos’s protocol gives therapists substantial discretion in how they treat their clients, which left some committee members concerned that trial participants might have received different therapy experiences depending on whether they received a drug or placebo. They pointed out that a good therapist could make a useless drug seem effective, and there is no way to disentangle the two effects. Panel members also worried about how therapists would be trained, and called for strong regulations to protect people from abuse by clinicians when under the influence of the drug.

Farchione says she hoped the advisory committee would help the agency to address these issues, particularly given that many other companies are studying psychedelic therapies that the FDA will eventually need to evaluate. “I think we are charting new territory, and we want to set it up right,” she says.

Further raising concerns, a report from the Institute for Clinical and Economic Review, a nonprofit group in Boston, Massachusetts, that analyses medical procedures, reported allegations that people who’d had bad experiences in the initial trials had been discouraged from participating in the follow up study. Lykos denied this at the committee meeting, and the FDA is conducting an investigation that will conclude before it makes a decision on the drug.

“I was absolutely shocked” by the committee’s vote, says psychiatrist Rachel Yehuda at the Icahn School of Medicine at Mount Sinai in New York City, who was not on the committee. “It was very disappointing.” She says the experts brought up good points over the eight-hour hearing, particularly about safety of people receiving treatment. She hopes that the FDA will look for ways to address these concerns instead of simply denying the drug. “I want us to have learned from the committee’s wisdom.” The FDA is expected to issue a decision in August.

In a statement Lykos said, “While we are disappointed in the vote, we are committed to continuing to collaborate with the FDA with their ongoing review of our [new drug application] over the coming weeks.”
 
Unfortunate but not so unexpected

Lingering concerns

But FDA scientists themselves had a number of concerns about Lykos’s studies, which they felt were lacking crucial psychological and physiological safety data. A major concern was the fact that participants — and their therapists — could almost always tell whether they had received MDMA or a placebo. An FDA report released ahead of the meeting called the data “challenging to interpret”.
Um yeah that's how you know you've taken something some real ****, there shouldn't be a shadow of a doubt
Other concerns included the fact that around 40% of the trial participants had taken illicit MDMA before the trial, potentially biasing the sample. And many sought other treatments — including psychedelic drugs — between the initial trial and the follow-up, suggesting that their symptoms might have continued and that their improvement might not have been due entirely to MDMA.
Funny how in other drug trials I've not heard of this... Wait you took another anti-depressant five years ago? So that means maybe this new one we're pushing out may not be the cause of this experimental new drug beating out placebo by an inch, I think we should shelf the whole matter! ...... said no one ever :ack:
Many of the advisory committee members’ questions centered on the role of psychotherapy.
God forbid you have to talk to someone suffering, gross, can't we just give them a pill so they can shut up & go back to work...
In a statement Lykos said, “While we are disappointed in the vote, we are committed to continuing to collaborate with the FDA with their ongoing review of our [new drug application] over the coming weeks.”
✊
 
This is the paper behind @Birdjaguar post of a buried elephant calf in the Cool Pics thread I commented on:

https://threatenedtaxa.org/index.php/JoTT/article/view/8826

Abstract​

Rampant environmental changes and forest destruction push elephants, both Asian and African, to explore human spaces to fulfil their dietary and ecological requirements and, consequently in shared spaces many ‘novel’ elephant behaviors come into the limelight. Elephant calf burial is reported in African literature but remains absent from the Asian context. We report calf burials by Asian Elephants in the eastern Himalayan floodplains of the northern Bengal landscape. The study area consists of fragmented forests, tea estates, agricultural lands, and military establishments. Tea estates form the majority of elephant corridors, and we explain the burial strategy of elephants in the irrigation drains of tea estates. We present five case reports of calf burials by elephants. We aimed to understand the perimortem strategy and postmortem behavior of the Asian Elephants. The major findings reflect that the carcasses were carried by trunks and legs for a distance before being buried in a ‘legs-upright-position’. We further investigated the underlying reason for calf deaths through postmortem examinations. Direct human intervention was not recorded in any of the five deaths. Through opportunistic observation, digital photography, fieldnotes, and postmortem examination reports, we suggest that the carcasses were buried in an abnormal recumbent style irrespective of the reason for the calf’s death. Through long-term observation, we further report that the elephants in this region clearly avoid the paths where carcasses were buried. We discuss and connect the literature of two distinct elephant species and also compare thanatological studies of other sentient nonhuman species.
 
"Life is mainly about being asleep."

Most Life on Earth is Dormant, After Pulling an ‘Emergency Brake’
Researchers recently reported the discovery of a natural protein, named Balon, that can bring a cell’s production of new proteins to a screeching halt. Balon was found in bacteria that hibernate in Arctic permafrost, but it also seems to be made by many other organisms and may be an overlooked mechanism for dormancy throughout the tree of life.

For most life forms, the ability to shut oneself off is a vital part of staying alive. Harsh conditions like lack of food or cold weather can appear out of nowhere. In these dire straits, rather than keel over and die, many organisms have mastered the art of dormancy. They slow down their activity and metabolism. Then, when better times roll back around, they reanimate.

Sitting around in a dormant state is actually the norm for the majority of life on Earth: By some estimates, 60% of all microbial cells are hibernating at any given time. Even in organisms whose entire bodies do not go dormant, like most mammals, some cellular populations within them rest and wait for the best time to activate.

“We live on a dormant planet,” said Sergey Melnikov, an evolutionary molecular biologist at Newcastle University. “Life is mainly about being asleep.”

But how do cells pull off this feat? Over the years, researchers have discovered a number of “hibernation factors,” proteins that cells use to induce and maintain a dormant state. When a cell detects some kind of adverse condition, like starvation or cold, it produces a suite of hibernation factors to shut its metabolism down.

Some hibernation factors dismantle cellular machinery; others prevent genes from being expressed. The most important ones, however, shut down the ribosome — the cell’s machine for building new proteins. Making proteins accounts for more than 50% of energy use in a growing bacterial cell. These hibernation factors throw sand in the gears of the ribosome, preventing it from synthesizing new proteins and thereby saving energy for the needs of basic survival.

Earlier this year, publishing in Nature, researchers reported the discovery of a new hibernation factor, which they have named Balon. The protein is shockingly common: A search for its gene sequence uncovered its presence in 20% of all cataloged bacterial genomes. And it works in a way that molecular biologists had never seen before.

Zzzzzzzzzzz. (May not render correctly in some countries.)

For more see...
 
https://www.popularmechanics.com/science/health/a60952102/tooth-regrowth-human-trials-japan/
While bones can regrow themselves when they break, teeth aren’t so lucky, and that leads to millions of people worldwide suffering from some form of edentulism, a.k.a. toothlessness.
Now, Japanese researchers are moving a promising, tooth-regrowing medicine into human trials—the first patients will be receiving the drug intravenously in September of this year.
If the trial is successful, the researchers hope the drug will become available for all forms of toothlessness sometime around 2030.
Scientists in Japan will begin human trials to trigger growth of teeth in adults.

They hope to have a working treatment by 2030.
 
Do not go without sleep when you want to remember stuff (like learning for exams?)

Sleep deprivation disrupts memory: here’s why

A crucial brain signal linked to long-term memory falters in rats when they are deprived of sleep — which might help to explain why poor sleep disrupts memory formation. Even a night of normal slumber after a poor night’s sleep isn’t enough to fix the brain signal.

These results, published today in Nature, suggest that there is a “critical window for memory processing”, says Loren Frank, a neuroscientist at the University of California, San Francisco, who was not involved with the study. “Once you’ve lost it, you’ve lost it.”

In time, these findings could lead to targeted treatments to improve memory, says study co-author Kamran Diba, a computational neuroscientist at the University of Michigan Medical School in Ann Arbor.

Firing in lockstep

Neurons in the brain seldom act alone; they are highly interconnected and often fire together in a rhythmic or repetitive pattern. One such pattern is the sharp-wave ripple, in which a large group of neurons fire with extreme synchrony, then a second large group of neurons does the same and so on, one after the other at a particular tempo. These ripples occur in a brain area called the hippocampus, which is key to memory formation. The patterns are thought to facilitate communication with the neocortex, where long-term memories are later stored.

One clue to their function is that some of these ripples are accelerated re-runs of brain-activity patterns that occurred during past events. For example, when an animal visits a particular spot in its cage, a specific group of neurons in the hippocampus fires in unison, creating a neural representation of that location. Later, these same neurons might participate in sharp-wave ripples — as if they were rapidly replaying snippets of that experience.

Previous research found that, when these ripples were disturbed, mice struggled on a memory test. And when the ripples were prolonged, their performance on the same test improved, leading György Buzsáki, a systems neuroscientist at NYU Langone Health in New York City, who has been researching these bursts since the 1980s, to call the ripples a ‘cognitive biomarker’ for memory and learning.

Researchers also noticed that sharp-wave ripples tend to occur during deep sleep as well as during waking hours, and that those bursts during slumber seem to be particularly important for transforming short-term knowledge into long-term memories5. These links between the ripples, sleep and memory are well-documented, but there have been few studies that have directly manipulated sleep to determine how it affects these ripples, and in turn memory, Diba says.

Wake-up call

To understand how poor sleep affects memory, Diba and his colleagues recorded hippocampal activity in seven rats as they explored mazes over the course of several weeks. The researchers regularly disrupted the sleep of some of the animals and let others sleep at will.

To Diba’s surprise, rats that were woken up repeatedly had similar, or even higher, levels of sharp-wave-ripple activity than the rodents that got normal sleep did. But the firing of the ripples was weaker and less organized, showing a marked decrease in repetition of previous firing patterns. After the sleep-deprived animals recovered over the course of two days, re-creation of previous neural patterns rebounded, but never reached levels found in those which had normal sleep.

This study makes clear that “memories continue to be processed after they’re experienced, and that post-experience processing is really important”, Frank says. He adds that it could explain why cramming before an exam or pulling an all-nighter might be an ineffective strategy.

It also teaches researchers an important lesson: the content of sharp-wave ripples is more important than its quantity, given that rats that got normal sleep and rats that were sleep-deprived had a similar number of ripples, he says.

Ripple effects

Buzsáki says that these findings square with data his group published in March that found that sharp-wave ripples that occur while an animal is awake might help to select which experiences enter long-term memory.

It’s possible, he says, that the disorganized sharp-wave ripples of sleep-deprived rats don’t allow them to effectively flag experiences for long-term memory. As a result, the animals might be unable to replay the neural firing of those experiences at a later time.

This means that sleep disruption could be used to prevent memories from entering long-term storage, which could be useful for people who have recently experienced something traumatic, such as those with post-traumatic stress disorder, Buzsáki says.


Neurons in the hippocampus 'cos florescent microscopy is cool
 
Last edited:
Top Bottom