Tim is right. I would estimate that 80% of the time, it is best to settle in place. Move the Worker (and Scout, if Expansionist) first, to see if there is a better place within 2 tiles. As a general rule, I would say *never* spend more than 2 turns moving before settling the first town; rarely move more than one tile.
FWIW, unless there is an obviously better spot just one tile away, I will settle in place on the first turn.
FWIW, unless there is an obviously better spot just one tile away, I will settle in place on the first turn.