I play with number of modmods - 4UC, Unique SS, Events&Decisions, Wonders for VP, Ancient Buildings Pack, Civic&Reform, EE, Industrial Buildings, Medieval & Renaissance Buildings, National Wonders Collection, Few More Buildings, Strategic Buildings, VP Bare Necessities, World Congress Reformation.
They do add to much quicker research, so (I play Epic speed) in TechCostChanges I set ResearchPercent to 225 (instead 150), in Classical 275, Medieval 350, R 450, EE 575, Industrial 750.
Everything seems OK, AI are able to keep up and eras to years also good.
Playing large map Planet Simulator with scarce resources.
When Egypt started to go over in science, I bought GS and expended him for research - I got immediate tech, then after choosing next tech in research small window at left upper corner I saw 350 000 research points out of 70 000 cost and somehow 48 turns to complete. Next turn all my 350 000 research points where gone, and I have 16 turns to complete research, but Egypt has no issues with buying GS (probably he has less cities 13 to my 25 ,and less Academies, and being AI doesn't get this big numbers). Using IGE just looked - he has 1135 science to my 5300 and still easy overtakes me, because my GS don't work. He already in Modern Era with 60 techs to my 56.
Think there is problem with big numbers - is 350 000 something that Civ 5 can't handle? Or what may I do?