What I'm most curious about is if the AI will use more than one core at a time. In Civ5, the graphics would, but the AI would not, so late-game on giant maps was slow, the same problem every version of Civ has had. I'd love to have the AI take advantage of modern CPUs - slashing the AI turn times by, say, 60% would do wonders for the type of map I prefer, and be far more effective than I could get by buying a new CPU. Most definitely, or at least as well as any other system can be. That's a pretty high-end setup. Most likely it will still run well enough, but with somewhat slower AI turn times. So as long as you aren't aiming to try the larger maps, you'll probably be okay.