People can get around it, but the medium isn't suited for it. If you have more than one Tweet, people can respond to individual Tweets. There's no way to reply to a "thread" of Tweets - all interactions are with the singular. This is relevant to not wanting to answer questions upfront, because someone could just go down your list of Tweet and troll every single one of them.
Commonly I get told this is what you accept for being on a public platform. Which would be fair enough, except it also applies to people asking questions in the first place. You accept the risk that the person simply isn't going to care, and can loudly profess to not care at any point (even pre-emptively). If people accepted both, I wouldn't mind so much, but in my experience as someone who uses the hellsite (a term of resigned, uh, endearment on Twitter), people who profess the former also demand immunity to the latter.