bryanw1995
Emperor
There must be at least 3 tiles between each city (not counting the cities themselves). This is one more tile than was required previously. It seems sort of insane at first, but I'd been forcing myself to play by the rule for the past week to see how it is, and it's actually not bad at all once you get used to it.
The most difficult thing about it is adjusting to it when planning your city locations, as I kept ending up accidentally planning for two cities an a space where I couldn't actually fit them (or one would prevent the other from getting a river spot or something like that).
I haven't finished a game yet with the patch, but I have to say that the 3 tiles between cities will probably be a pretty big hindrance to the AI. So many of their other changes have promoted "normal" empires that they might eventually go back to 2 tiles.