I've been working on a HUGE region, "Pancharis," with a theme for each of the sections. Smack dab in the middle is Pancharis City, the capital. The western regions, the Land of Gales, is filled with mountains and hills. The southern regions, the Land of Flames, is filled with the remains of meteor strikes and eruptions. The eastern regions, the Land of Tides, is filled with rivers, lakes, and vast oceans. Finally, the northern region, the Land of Plains, is completely flat.
The West prides military prowess and hard labor. The South is a land of contrast, where the invigoration of life is as valued as the solemness of death. The East has a strong belief in merchant pursuits, but also compassion for one's fellow man. Finally, the North favors intellectual pursuits and using reason and planning in any situation.
It is the North that I will show.
Cities in the North are frequently named for scientists or industrialists, individuals who maximised the Earth's potential. Here, we can see the northern industrial center of Carnegie, and its southern neighbor, residential Asperger. While the north racks up huge profits due to a lack of services apart from fire, the south tends to be a budget balancer, creating just enough to get by, while also providing a wealth of security, education, and healthcare services to its people.
You may say that the cities are heavily grid-based. That is the point - the technocratic north despises randomness and inefficiency, and so has built a massive set of avenues; roads are not worth the investment for their grand ambitions.
With an educational base having formed, it is readily apparent that the Sons of the Tortoise are ready to take their place as Pancharis' intellectual elite. 46.5 citizens live in Asperger, which has begun to develop high-rises in the South. Yet, traffic issues are non-existent thanks to a robust subway system, and heavy duty roads!
Now of course, the golden question - where will the Land of Plains go next? Will a massive metropolis sprout in the center of the North, or will Asperger continue to steal the show, until it easily reaches half a million people? (Possible according to my estimates) There's a raging demand of high-tech industries, but that can wait until later...
The region as a whole is 52 x 52. That would be 13 large cities if they were laid from end to end.