Well, my old standard medic loadout is Overdose/Vita Saw, for the least fighty healing medic you'll ever see... but sometimes I switch it up and go Blutsauger/Amputator when I feel like being a little more aggressive. Lately I've been using the Blutsauger/Vita Saw, as the movement bonus of the Overdose isn't that great, and I've gradually improved my aim to the point where my aim is good enough for the Blutsauger to be a good weapon.
So generally I don't play a combat medic, but I'm not at all afraid to get into duels with scouts and spies.