Take India, crush the Tamils, and spread to Indochina. Ideally, you settle Hanoi, which is outside the flipzones of Khmer and Siam. Then crush them as well amphibiously and resettle/take Ayutthaya. Trade tech with China and Corea. Keep espionage slider on China. You only worry about the Mughal spawn and possible subcontinental respawns. Keep an eye out for opportunity in China. If they need protection from Mongols, vassalize them. If Mongols are about to win and they won't vassalize, DoW and take as many Chinese cities as possible, don't let the Mongols get any profit.
Hope for a weak Russia and China that you can cultivate to grow; as they are ideal vassals, and you will all share a common enemy in Mongols. How you play and how the AIs play during Mongol spawn is the most critical juncture of your game. It also would make for great narrative material, with Persia at the head of a Eurasian Security Pact.
I hope that helped.