No.
There is no Oxford comma, which implies that it is one item.
While the comma isn't necessary, it's omission can have very real implications.
For a more obvious example on how a simple comma can mess with meaning, if I write a letter and say, "To Sid Meir, my brother and my boss..." - it sounds like Sid Meir is my brother and my boss. If I instead write, "To Sid Meir, my brother, and my boss.." it sounds like I'm writing to three people.
While theoretically the above release could be interpreted both ways, it's not nearly sufficient enough in itself to suggest that leaders are separate from civilizations. Personally, I'd maintain that the exclusion of the comma is indicative of 'Civilizations and Leaders' being a single item in the list.