About none of those methods you said are used for anti-piracy or hardly at all. Others exits for other reasons and pirates benefit from almost all them (maybe not support etc). So there is nothing I need to ask for myself.
According to the recent study Denuvo increases profits. So it is totally irrelevant if there is still ways left to pirate.
I guess this was addressed by irdeto somewhat same way in RPS interview as earlier in this thread.
What is ration of failed implementations vs working implementations? Irdeto themselves also referenced to experience of implementer and Firaxis and 2K have experience.
In my categorisation "fear" would too strong. I think I would categorize it as footnote.
They do have experience, not the same dev team AFAIK, but I agree it's logical to suppose they can share the experience. OTOH the fear of Firaxis optimizations is based on experience with civ6, a game that could run very large maps at launch on a 980Ti and could not launch the same maps at the end of the development cycle on a 3080 (I've not tried on my current CG, but people are still reporting issues on 40x0)
And if Denuvo requires a good implementation, that also means it requires dev time, and testing. They can't put the check in a few functions only because it would be less hard to crack it by replacing the functions (and it was cracked that way, he's saying it in the interview), and need to put it in functions that are not called too many time to prevent the impact on performance to become visible.
How much dev time exactly, we don't know, but enough for Amplitude to abandon Denuvo a few months before release because they couldn't implement it in a way that didn't impact performances (and the Giant Earth Map works fine on HK, maybe unrelated, but just saying)
That development time could have been used on a low cost feature than Hotseat for example. I'm sure 2K can calculate that they will make more money preventing piracy in the first months than adding a feature which has a relatively low demand at launch, but in the end it's us, players, who are losing something in the process, with a game that cost the same or more than other games without Denuvo.