AIDS .. actually cured... by scientists ... in simian trials

JerichoHill

Bedrock of Knowledge
Joined
Nov 23, 2005
Messages
10,384
Location
Washington DC
http://www.11alive.com/news/article_news.aspx?storyid=93439

The world could have a new vaccine designed to kill the AIDS virus in as little as three to four years according to an Atlanta-based group working on the vaccine.

It is a scientific advance that could save tens of millions of lives, and it is being developed on the campus of Emory University.

The work has been going on quietly for the last 15 years. But now it appears headed for the bell lap in the race to prevent the disease.

And the Atlanta-based group may be way ahead of the rest of the world.

The GeoVax lab at Emory is smaller than many garages. And yet the small modular building may be where the battle to end the reign of one the world's biggest killers could be won with a vaccine to prevent AIDS.

"We're getting results back that indicate we're getting very strong immune responses in these individuals these people who received our vaccine," said Don Hildebrand, the president and CEO of GeoVax Inc., the company spearheading the research in collaboration with Emory, the Centers for Disease Control, and the National Institutes of Health.

The vaccine uses a decoy virus with some of the genetic material of the aids virus but not enough for anyone to ever get the disease itself from the shot, according to Dr. Harriet Robinson, Ph. D., of the Emory Vaccine Center.

"It exposes your immune system to a pathogen like a virus or bacteria so before you've seen it you set up memory cells,” Dr. Robinson said, “and then these memory cells mobilize should you get the actual infection."

The test trials have been so successful that the vaccine is now more than a year ahead of schedule.

"Actually another two trials are starting later this year using different combinations of our vaccine and different administration programs,” said GeoVax CEO Hildebrand. “And following that presuming everything goes well we'll be starting a phase two program at the end of the year."

The vaccine works using a one-two pharmaceutical punch to prime the body then kill the virus.

“It raises both antibodies that can block the virus and it raises white blood cells called t cells that can kill the virus infected cells,” said Dr. Robinson. “So it really has two methods of controlling an HIV/AIDS infection once it enters the body."

The vaccine’s success with the simian AIDS virus has been nothing short of remarkable. Not only did the vaccine prevent the infection, it kept it under control for the monkeys that already had it, putting it in a kind of remission.

Researchers believe the same benefits await human subjects.
 
Yeah but how long until its available to the public and in wide numbers?

Vaccines have to go through tons and tons of testing before released onto the market dont they?

4 years sounds very short...
 
"It exposes your immune system to a pathogen like a virus or bacteria so before you've seen it you set up memory cells,” Dr. Robinson said, “and then these memory cells mobilize should you get the actual infection."
Yes that is what a vaccine does. What makes this vaccine so revolutionary?
 
Yes that is what a vaccine does. What makes this vaccine so revolutionary?

It works?

Anyway, is it for preventing AIDS or for stopping it killing you when you already have it?
 
I suppose we can start focusing on Global Warming now ;)

Seriously, this is great news.
 
This is good news yes, but then the battle will begin over who manufactures all the billion vaccines, if theyre allowed to charge for it, if not how theyre recompensed etc. I bet it will be ready to go for years before anyone is administered the vaccine.
 
I'm (figuratively) sure someone aleady has ownership rights.
 
I'm (figuratively) sure someone aleady has ownership rights.
Yeah but then theres the mass production on a global scale, distribution. All of thats going to cost alot of money, so theres going to be a ton of wrangling and haggling and legal battles and all of that, before anyone in need gets a shot.
 
It works?

Anyway, is it for preventing AIDS or for stopping it killing you when you already have it?

The vaccine&#8217;s success with the simian AIDS virus has been nothing short of remarkable. Not only did the vaccine prevent the infection, it kept it under control for the monkeys that already had it, putting it in a kind of remission.<---- is what the article said, so mainly a preventitive type thing but stops it killing you also.
 
Bright day
Finally. You know; one would think, that with the number of peole who are immune to AIDS, they would have gotten it earlier.
 
I really want to believe this, but I have a hard time doing it. It just seems too good.
 
If it actually works; it seems like we come across one of these stories every few months and it never pans out.
 
I hope no one tries to make money out of this.
Fleecing money out of starving people in 3rd world countries seems immoral at best
 
Why not believe this? Umm, its Emory, a pretty darn good medical university who works with the CDC.

I dont know who is going to hold the patent, but given Emory's liberal slant, I don't seen them gouging it.

And yes, testing takes a long time. They are on human trials now.
Hence, four years
 
i would hope someone like mr. gates would put his money where his mouth is and buy up a bunch to give to africa.

of course, provided this works.
 
Why not believe this? Umm, its Emory, a pretty darn good medical university who works with the CDC.

Believe me, I want to believe it. It's just that it sounds almost to good to be true.

Things like this doesn't happen just every day.
 
Kinda of topic, but whatever became of that diabetes treatment from Duke a few years ago?
 
It is for real - in a sense :)
Harriet Robinson has a good history in HIV research and especially in HIV vaccine research. They did show some promising results in recent years (though the actually published efficiency of this particular vaccine was only 63&#37; half a year ago). But they are not the only ones with vaccines who have completed preclinical trials/moved to phase 1 clinical trials and one should use caution when looking into the future. While promising they have up to now only shown that this vaccine works against SIV (simian immunodeficiency virus) or SIV/HIV-1 hybrids. HIV-1 which also causes simian infections has either not been tested by them or it has not worked... Also HIV-2 which is responsible for a significant portion of human infections does not infect simians at all so that it is by no means clear whether this vaccine will work against this as well. Press releases by pharmaceutical companies (such as GeoVax) are also always extremely positive on their prospects so that one should wait before claiming AIDS cured - it is not yet and will probably take a while if it is ever achieved.
Finding a vaccine that actually works though would be the holy grail of todays immunology - it will probably be cheaper to administer vaccines than to treat people for their whole life with antivirals... So: promising? Yes. Good news? Yes. A Cure? Nope.
 
Back
Top Bottom