Sure. I think it's worth noting that sometimes that doesn't happen though.
Sometimes 6 barbarians raid your capital on turn 10, sometimes the rest of your luxuries are on the other side of mountains. Not every start will be balanced, that's the point of civ!
A typical start on a standard size is their are about 8 copies of your luxury that will be grouped somewhat geographically close to each other. Your luxury can be anything discussed in this thread, except marble (whales starts exist on Pangea, I'm 100% sure).
For the monopoly, hopefully you can get 3 copies in your capital, and two copies in another city, to reach 5 and get a quick monopoly. This is very powerful on coral, pearls, silver, wine, incense, citrus, cocoa, cinnamon and tobacco. The other monopolies benefit less so starting this way isn't as great (though still useful).
On huge map size, its hopefully 3 cities, sometimes 4 are need.
On small, its usually two.
Legendary start usually increases the total quantity of luxuries by 1 which can change the above map. Strategic balance won't affect it. Sparse resources will cause all sorts of mayhem with monopolies.
All the above are generally true for Continents, Pangea, and Oval, which are by the far the most commonly played maps. Fractal is similar to this but with more oceans invovled. Occasionally your luxuries start grouped far away from you, usually because there are mountains or an ocean in between you. But that's really rare, like 1% of games at most.
I've played a lot of VP, this is what you can normally expect on the commonly played maps. Most toher maps follow it pretty closely as well. Yes sometimes it doesn't happen (but if you play one of these map scripts and don't get a regional, really its a bug). We have to look at what's common when balancing, this is what's common with resources.