What.
I think it's more akin to moving into the huge 50 room extension that you have always had but never been in to.
The point is to move away from Earth, not to settle more dirt (or mud). Ultimately it comes down to what people will find exciting enough to motivate them to spend all their money to achieve it. If enough of them become convinced that building a colony on the bottom of the ocean and watch... pale weird creatures eat each other or something, is a good idea, well, then it will happen.
In my perspective, colonizing space offers humanity something infinitely more exciting because once you learn how to successfully move off Earth and establish a self-sustaining colony somewhere else in space, you basically open the rest of the universe for more human exploration/colonization.
In case of Mars and Venus colonists can be very numerous because these planets are close.
I doubt it. Moving just one warm human body plus the gear to sustain it to, say, Mars, is incredibly energy intensive. This means that the owner of the body either needs to be extraordinarily indispensable (i.e. possessing of skills that make him or her mission critical), or extraordinarily rich to pay for all of it him/herself.
Unless some sort of magic technology is invented that makes space travel several orders of magnitude less energy intensive, space colonization will be an effort physically involving only a tiiiiiiny fraction of humanity - by that I mean thousands, tens of thousands of people at maximum.
Even if we managed to somehow move a million people to Mars (completely unrealistic with present or near-term technology), these million people would represent only 1/7000th of the overall human population.
But in case of extrasolar planets sending a Space Ark with up to 250,000 people to each planet is OK.
Again, completely unrealistic. I spoke about the insane energy intensiveness of space travel inside the Solar System. Now magnify that by about 100,000 and you get how impossibly difficult it is to move something to another star system in something that's not measured in geologic time.
For this reason, sending an interstellar expedition will probably involve just a few people (and lots of frozen embryos). In fact, some people believe it would be better to send just robots and the frozen embryos...
We already have such technology. We can build space crafts propelled by nuclear explosions (see Project Orion)
There is a world of difference between knowing something is possible on paper and actually being able to do it. Building an interstellar ship using nuclear explosions for propulsion is of course
possible; whether it is a good and practical idea remains to be demonstrated.
You mean the substance we've so far managed to manufacture a few picograms of? I'll quote Wiki to save myself the time of explaining why this is a bit of a problem:
The biggest limiting factor in the large-scale production of antimatter is the availability of antiprotons. Recent data released by CERN states that, when fully operational, their facilities are capable of producing ten million antiprotons per minute.[38] Assuming a 100% conversion of antiprotons to antihydrogen, it would take 100 billion years to produce 1 gram or 1 mole of antihydrogen.
(...) in 1999, NASA gave a figure of $62.5 trillion per gram of antihydrogen
And of course we have no feasible way of storing that antihydrogen - magnetic traps only work with ionized antihydrogen and then you can store only microscopic amounts, and neutral antihydrogen doesn't respond to magnetic containment.
Both these technologies can enable us very fast speed of space travel, significant fractions of the speed of light.
Sure, once you overcome the OVERWHELMINGLY daunting technological challenges of bringing them from paper (or Michio Kaku's 'documentary' on Discovery channel) to reality.
This is why you don't build space arks housing hundreds of thousands of people and propel them to relevant fractions of the speed of light. The amount of anti-matter fuel, even assuming you can somehow store it and efficiently use in propulsion, needed for that would be measured in thousands of tonnes. There is no currently known way of making that possible.
So, I suggest aiming little lower... you know, somewhere where we can actually reach within one human lifespan without needing to invent magic first.