I have no idea. I'm sure that with the 'radioactive data' etc, us evilutionists will be able to force-fit the mutation rate into something much longer than 4000 years. I have NO ability to judge the data, though, so I'll just assume I have no leg to stand on - regardless of my opinion. Of course, I could probably just wiki this information, but that would be regurgitation, not understanding. I've heard that the genetic 'Adam' is younger than the genetic 'Eve', by many, many years.
I think this was the weakness in my argument. I was assuming (in my statements) that the oocytes were released in a step-wise fashion from a set group.
It looks like the healthiest are released, ones that have met some type of selection process (thus reducing the accumulated degeneration below the threshold where internal natural selection can take hold).
I still think that extended efforts to get women to have children in their late 30s (using medical technologies) will lead to children with weaker genomes, unless we select out the weaker eggs better (which is tough, since anything more than visual examination is hard on the eggs) Of course, if we just naturally selected for women bearing children in their late 30s (prohibited reproduction until then) we'd select for longevity genes. Much like we saw with Dr. Michael Rose's work with fruitflies.